Famoxadone
Famoxadone is a fungicide to protect agricultural products against various fungal diseases on fruiting vegetables, tomatoes, potatoes, curcurbits, lettuce and grapes.<ref name=EPA>Famoxadone Pesticide Fact Sheet, United States Environmental Protection Agency</ref> It is used in combination with cymoxanil.<ref name=EPA/><ref name="UGA-ext">{{#invoke:citation/CS1|citation |CitationClass=web }}</ref> Famoxadone is a QoI, albeit with a chemistry different from most QoIs. (It is an oxazolidine-dione while most are strobilurins.)<ref name="Knight-et-al-1997" /><ref name="Schepers-Cooke-2015" /><ref name="FRAC-MoAs">{{#invoke:citation/CS1|citation |CitationClass=web }}</ref> It is commonly used against Plasmopara viticola,<ref name="Knight-et-al-1997" /> Alternaria solani,<ref name="Knight-et-al-1997" /><ref name="Schepers-Cooke-2015">Template:Cite book</ref> Phytophthora infestans,<ref name="Knight-et-al-1997" /><ref name="Schepers-Cooke-2015" /> and Septoria nodorum.<ref name="Knight-et-al-1997">Template:Cite journal</ref><ref name="Schepers-Cooke-2015" />
Molecular interactionEdit
Famoxadone is of lesser interaction strength at the Qp pocket than some other QoIs, for example, azoxystrobin. This is because azoxystrobin and such interact more centrally in the Qp pocket than does famoxadone.<ref name="Cramer-et-al-2006">Template:Cite journal</ref>
Resistance managementEdit
Although it has a different chemistry, famoxadone shows full cross-resistance with the rest of the main FRAC group 11<ref name="Schepers-Cooke-2015" /> that it belongs to, which is almost entirely strobs. It has not shown cross-resistance with the 11A subgroup however. As with all QoIs there is a high risk of resistance development and so pesticide stewardship is important.<ref name="FRAC-MoAs" /><ref name="Schepers-Cooke-2015" />
Populations of P. infestans and A. solani in northern and western Europe are not known to be resistant to famoxadone.<ref name="Schepers-Cooke-2015" />
Great Britain approval withdrawnEdit
On June 30 2024, approval for famoxadone's use in Great Britain was withdrawn by the Health and Safety Executive due to the risk it presents to birds.<ref>{{#invoke:citation/CS1|citation |CitationClass=web }}</ref> Its use was already banned in the European Union, and there was in 2024 concern about the levels of allowed residue particularly on table grapes being too high.<ref>{{#invoke:citation/CS1|citation |CitationClass=web }}</ref>