Hounsfield scale

Template:Short description The Hounsfield scale (Template:IPAc-en Template:Respell), named after Sir Godfrey Hounsfield, is a quantitative scale for describing radiodensity. It is frequently used in CT scans, where its value is also termed CT number.

DefinitionEdit

The Hounsfield unit (HU) scale is a linear transformation of the original linear attenuation coefficient measurement into one in which the radiodensity of distilled water at standard pressure and temperature (STP) is defined as 0 Hounsfield units (HU), while the radiodensity of air at STP is defined as −1000 HU. In a voxel with average linear attenuation coefficient <math>\mu</math>, the corresponding HU value is therefore given by:<ref>Template:Cite journal</ref><ref>Template:Cite journal</ref>

<math display=block>HU = 1000\times\frac{\mu - \mu_{\textrm{water}}}{\mu_{\textrm{water}} - \mu_{\textrm{air}}}</math>

where <math>\mu_{\textrm{water}}</math> and <math>\mu_{\textrm{air}}</math> are respectively the linear attenuation coefficients of water and air.

Thus, a change of one Hounsfield unit (HU) represents a change of 0.1% of the attenuation coefficient of water since the attenuation coefficient of air is nearly zero.<ref name="IAEADiagRadPhys">Template:Cite book</ref>Template:Rp

Calibration tests of HU with reference to water and other materials may be done to ensure standardised response. This is particularly important for CT scans used in radiotherapy treatment planning, where HU is converted to electron density.<ref>Template:Cite book</ref> Variation in the measured values of reference materials with known composition, and variation between and within slices may be used as part of test procedures.<ref name="IAEADiagRadPhys" />Template:Rp<ref>Template:Cite book</ref>

RationaleEdit

The above standards were chosen originally to encode the radiodensity of organic tissues relative to water for 12-bit processing on clinical CT scanners.<ref>Template:Cite journal</ref> A 12-bit encoding corresponds to 4096 (<math>2^{12}</math>) values, where the range (–1024 to 3071) encompasses HU values for air, soft tissue and bone.

Values for different body tissues and materialEdit

File:CT Scan Thorax Lung -700 HU Window Level.jpg

CT scan of the thorax with window level set to -700 HU (lung)

File:CT Scan Thorax Air -1000 HU Window Level.jpg

CT scan of the thorax with window level set to -1,000 HU (air)

File:CT Scan Thorax Water 0 HU Window Level.jpg

CT scan of the thorax with window level set to 0 HU (water)

File:CT Scan Thorax Liver 60 HU Window Level.jpg

CT scan of the thorax with window level set to 60 HU (liver)

HU-based differentiation of material applies to medical-grade dual-energy CT scans but not to cone beam computed tomography (CBCT) scans, as CBCT scans provide unreliable HU readings.<ref name="DEVOS">Template:Cite journal</ref>

Values reported here are approximations. Different dynamics are reported from one study to another.Template:Cn

Exact HU dynamics can vary from one CT acquisition to another due to CT acquisition and reconstruction parameters (kV, filters, reconstruction algorithms, etc.). The use of contrast agents modifies HU as well in some body parts (mainly blood).

Substance		HU
Air		−1000
Fat		−120 to −90<ref name="Lepor2000" />
Soft tissue on contrast CT		+100 to +300
Bone	Cancellous	+300 to +400<ref name="BirurPatrick2017">Template:Cite journal</ref>
Bone	Cortical	+500 to +1900<ref>Template:Cite journal</ref><ref name="BirurPatrick2017" /><ref>Template:Cite journal</ref>
Subdural hematoma	First hours	+75 to +100<ref name="Rao2016">Fig 3 in: Template:Cite journal</ref>
	After 3 days	+65 to +85<ref name="Rao2016" />
	After 10–14 days	citation	CitationClass=web }}</ref>
Other blood	Unclotted	+13<ref name="fosbinder2011">Template:Cite book</ref> to +50<ref>Template:Cite book</ref>
Other blood	Clotted	+50<ref name="fast2006">Template:Cite book</ref> to +75<ref name="fosbinder2011" /><ref name="fast2006" />
Pleural effusion	Transudate	+2 to +15 <ref name="CulluKalemci2013">Template:Cite journal</ref>
Pleural effusion	Exudate	+4 to +33<ref name="CulluKalemci2013" />
Other fluids	Chyle	−30<ref>Page 342 in: Template:Cite book</ref>
	Water	0
	Urine	−5 to +15<ref name="Lepor2000">Page 83 in: Template:Cite book</ref>
	Bile	−5 to +15<ref name="Lepor2000" />
	CSF	+15
	Abscess / Pus	0<ref name="ecr">Template:Cite journal</ref> or +20,<ref name="SasakiMiyata2014">Template:Cite journal</ref> to +40<ref name="SasakiMiyata2014" /> or +45<ref name="ecr" />
	Mucus	0<ref>Template:Cite journal Template:Dead link</ref> - 130<ref name="GaetaVinci2001">Template:Cite journal</ref> ("high attenuating" at over 70 HU)<ref>Template:Cite journal</ref><ref name="AgarwalSehgal2016">Template:Cite journal</ref>
Parenchyma	Lung	−700 to −600<ref>Template:Cite book</ref>
	Kidney	+20 to +45<ref name="Lepor2000" />
	Liver	60 ± 6<ref>Template:Cite book</ref>
	Lymph nodes	+10 to +20<ref>Template:Cite book</ref>
	Muscle	+35 to +55<ref name="Lepor2000" />
	Thymus	+20 to +40 in children<ref name="givel2012">Template:Cite book</ref> +20 to +120 in adolescents<ref name="givel2012" />
	White matter	+20 to +30
	Grey matter	+37 to +45
Gallstone	Cholesterol stone	+30 to +100<ref name="pmid2121509">Template:Cite journal</ref>
Gallstone	Bilirubin stone	+90 to +120<ref name="pmid2121509" />
Foreign body<ref name="BolligerOesterhelweg2009">Template:Cite journal</ref>	Windowpane glass	+500
	Aluminum, tarmac, car window glass, bottle glass, and other rocks	+2,100 to +2,300
	Limestone	+2,800
	Copper	+14,000
	Silver	+17,000
	Steel	+20,000
	Gold, steel, and brass	+30,000 (upper measurable limit)
Earwax		<0

A practical application of this is in evaluation of tumors, where, for example, an adrenal tumor with a radiodensity of less than 10 HU is rather fatty in composition and almost certainly a benign adrenal adenoma.<ref>{{#invoke:citation/CS1|citation |CitationClass=web }}</ref>