Keratin 10
Template:Short description Template:Infobox gene Keratin, type I cytoskeletal 10 also known as cytokeratin-10 (CK-10) or keratin-10 (K10) is a protein that in humans is encoded by the KRT10 gene.<ref name="pmid2461420">Template:Cite journal</ref><ref name="pmid16831889">Template:Cite journal</ref><ref name="entrez">{{#invoke:citation/CS1|citation |CitationClass=web }}</ref> Keratin 10 is a type I keratin.
FunctionEdit
Keratin-10 is a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21.<ref name="entrez"/>
InteractionsEdit
Keratin 10 has been shown to interact with AKT1.<ref name=pmid11585925>Template:Cite journal</ref>
See alsoEdit
- 34βE12 (keratin 903)
ReferencesEdit
Further readingEdit
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