Template:Short descriptionTemplate:Human-centric Template:Infobox microanatomy Template:Gastrointestinal wall series A mucous membrane or mucosa is a membrane that lines various cavities in the body of an organism and covers the surface of internal organs. It consists of one or more layers of epithelial cells overlying a layer of loose connective tissue. It is mostly of endodermal origin and is continuous with the skin at body openings such as the eyes, eyelids, ears, inside the nose, inside the mouth, lips, the genital areas, the urethral opening and the anus. Some mucous membranes secrete mucus, a thick protective fluid. The function of the membrane is to stop pathogens and dirt from entering the body and to prevent bodily tissues from becoming dehydrated.
StructureEdit
The mucosa is composed of one or more layers of epithelial cells that secrete mucus, and an underlying lamina propria of loose connective tissue.<ref name="britan">Template:Cite encyclopedia</ref> The type of cells and type of mucus secreted vary from organ to organ and each can differ along a given tract.<ref name=Guyton2005>Template:Cite book</ref><ref>Template:Cite book</ref>
Mucous membranes line the digestive, respiratory and reproductive tracts and are the primary barrier between the external world and the interior of the body; in an adult human the total surface area of the mucosa is about 400 square meters while the surface area of the skin is about 2 square meters.<ref name="Sompayrac2012">Template:Cite book</ref>Template:Rp Along with providing a physical barrier, they also contain key parts of the immune system and serve as the interface between the body proper and the microbiome.<ref name=Guyton2005/>Template:Rp
ExamplesEdit
Some examples include:Template:Cn
- Endometrium: the mucosa of the uterus
- Gastric mucosa
- Intestinal mucosa
- Nasal mucosa
- Olfactory mucosa
- Oral mucosa
- Penile mucosa
- Respiratory mucosa
- Vaginal mucosa
- Frenulum of tongue
- Anal canal
- Conjunctiva
DevelopmentEdit
Developmentally, the majority of mucous membranes are of endodermal origin.<ref>{{#invoke:citation/CS1|citation |CitationClass=web }}</ref> Exceptions include the palate, cheeks, floor of the mouth, gums, lips and the portion of the anal canal below the pectinate line, which are all ectodermal in origin.<ref>Template:Cite book</ref><ref>Template:Cite book</ref>
FunctionEdit
One of its functions is to keep the tissue moist (for example in the respiratory tract, including the mouth and nose).<ref name=Guyton2005/>Template:Rp It also plays a role in absorbing and transforming nutrients.<ref name=Guyton2005/>Template:Rp Mucous membranes also protect the body from itself. For instance, mucosa in the stomach protects it from stomach acid,<ref name=Guyton2005/>Template:Rp and mucosa lining the bladder protects the underlying tissue from urine.<ref name=Fry2016rev>Template:Cite journal</ref> In the uterus, the mucous membrane is called the endometrium, and it swells each month and is then eliminated during menstruation.<ref name=Guyton2005/>Template:Rp
NutritionEdit
Niacin<ref name=Guyton2005/>Template:Rp and vitamin A are essential nutrients that help maintain mucous membranes.<ref>{{#invoke:citation/CS1|citation |CitationClass=web }}</ref>
See alsoEdit
- Alkaline mucus
- Mucin
- Mucociliary clearance
- Mucocutaneous boundary
- Mucosal immunology
- Mucosal melanoma
- Rete pegs
ReferencesEdit
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