Thiolysis

Thiolysis is a reaction with a thiol (R-SH) that cleaves one compound into two.<ref>Template:Cite journal</ref> Thiolysis involves the addition of coenzyme A to one of the products. This reaction is similar to hydrolysis, which involves water instead of a thiol.<ref>Template:Citation</ref> This reaction is seen in β-oxidation of fatty acids.<ref>Template:Cite journal</ref> The depolymerisation of condensed tannins with the use of benzyl mercaptan as nucleophile is also called thiolysis.<ref>Template:Cite journal</ref>

File:FattyAcid-MB-Thiolysis.png

Example of thiolysis (thiol: CoA-SH)