Editing Atrial flutter (section)

{{Short description|Abnormal heart rhythm beginning in the atria}}
{{Distinguish|Atrial fibrillation}}
{{Infobox medical condition (new)
| name            = Atrial flutter
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| field           = [[Cardiology]]
| image           = Atrial_flutter34.svg
| caption         = Atrial flutter with varying A-V conduction (5:1 and 4:1)
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| diagnosis       = [[Electrocardiography]]
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<!-- Definition and symptoms -->
'''Atrial flutter''' ('''AFL''') is a common [[cardiac arrhythmia|abnormal heart rhythm]] that starts in the [[atrium (anatomy)|atrial chambers]] of the [[heart]].<ref name="Sawhney2009"/>  When it first occurs, it is usually associated with a [[tachycardia|fast heart rate]] and is classified as a type of [[supraventricular tachycardia]] (SVT).<ref name="Link2012">{{cite journal|last1=Link|first1=MS|title=Clinical practice. Evaluation and initial treatment of supraventricular tachycardia|journal=New England Journal of Medicine|date=October 2012|volume=367|issue=15|pages=1438–48|doi=10.1056/NEJMcp1111259|pmid=23050527}}</ref> Atrial flutter is characterized by a sudden-onset (usually) regular abnormal heart rhythm on an [[electrocardiogram]] (ECG) in which the heart rate is fast. Symptoms may include [[palpitation|a feeling of the heart beating too fast, too hard, or skipping beats]], chest discomfort, [[dyspnea|difficulty breathing]], a feeling as if one's stomach has dropped, a feeling of being light-headed, or [[Syncope (medicine)|loss of consciousness]].

<!-- Cause and Pathophysiology -->
Although this abnormal heart rhythm typically occurs in individuals with cardiovascular disease (e.g., [[hypertension|high blood pressure]], [[coronary artery disease]], and [[cardiomyopathy]]) and [[diabetes mellitus]], it may occur spontaneously in people with otherwise normal hearts. It is typically not a stable rhythm and often degenerates into [[atrial fibrillation]] (AF).<ref name="Bun2015"/>  But rarely does it persist for months or years. Similar to the abnormal heart rhythm atrial fibrillation, atrial flutter also leads to poor contraction of the atrial chambers of the heart. This leads to the pooling of the blood in the heart and can lead to the formation of [[thrombus|blood clots]] in the heart, which poses a significant risk of [[embolus|breaking off and traveling through the bloodstream]], resulting in [[stroke]]s.

<!-- Prevention and Treatment -->
A supraventricular tachycardia with a ventricular heart rate of 150 beats per minute is suggestive (though not necessarily diagnostic) of atrial flutter. Administration of [[adenosine]] in the vein (intravenously) can help medical personnel differentiate between atrial flutter and other forms of supraventricular tachycardia.<ref name="Link2012"/> Immediate treatment of atrial flutter centers on slowing the heart rate with medications such as [[beta blocker]]s (e.g., [[metoprolol]]) or [[calcium channel blocker]]s (e.g., [[diltiazem]]) if the affected person is not having chest pain, has not lost consciousness, and if their blood pressure is normal (known as stable atrial flutter). If the affected person is having chest pain, has lost consciousness, or has [[hypotension|low blood pressure]] (unstable atrial flutter), then an urgent [[cardioversion|electrical shock to the heart]] to restore a normal heart rhythm is necessary. Long-term [[anticoagulation|use of blood thinners]] (e.g., [[warfarin]] or [[apixaban]]) is an important component of treatment to reduce the risk of blood clot formation in the heart and resultant strokes.<ref name="Bun2015"/><ref name="Vadmann2015">{{cite journal|last1=Vadmann|first1=H|last2=Nielsen|first2=PB|last3=Hjortshøj|first3=SP|last4=Riahi|first4=S|last5=Rasmussen|first5=LH|last6=Lip|first6=GY|last7=Larsen|first7=TB|title=Atrial flutter and thromboembolic risk: a systematic review|journal=Heart|date=September 2015|volume=101|issue=18|pages=1446–55|doi=10.1136/heartjnl-2015-307550|pmid=26149627|s2cid=26126493}}</ref> [[Antiarrhythmic|Medications used to restore a normal heart rhythm (antiarrhythmics)]] such as [[ibutilide]] effectively control atrial flutter about 80% of the time when they are started but atrial flutter recurs at a high rate (70–90% of the time) despite continued use.<ref name="Sawhney2009">{{cite journal|last1=Sawhney|first1=NS|last2=Anousheh|first2=R|last3=Chen|first3=WC|last4=Feld|first4=GK|title=Diagnosis and management of typical atrial flutter|journal=Cardiology Clinics|date=February 2009|volume=27|issue=1|pages=55–67, viii|doi=10.1016/j.ccl.2008.09.010|pmid=19111764|type=Review}}</ref> Atrial flutter can be treated more definitively with a technique known as [[catheter ablation]]. This involves the insertion of a catheter through a vein in the groin which is followed up to the heart and is used to identify and interrupt the electrical circuit causing the atrial flutter (by creating a small burn and scar).

<!-- Epidemiology -->
Atrial flutter was first identified as an independent medical condition in 1920 by the British physician [[Thomas Lewis (cardiologist)|Sir Thomas Lewis]] (1881–1945) and colleagues.<ref>{{cite journal |vauthors=Lewis T, Feil HS, Stroud WD | title=Observations upon flutter, fibrillation, II: the nature of auricular flutter | journal=Heart | year=1920 | volume=7 | page=191}}</ref> AFL is the second most common pathologic supraventricular tachycardia but occurs at a rate less than one-tenth of the most common supraventricular tachycardia (atrial fibrillation).<ref name="Link2012"/><ref name="Bun2015">{{cite journal|last1=Bun|first1=SS|last2=Latcu|first2=DG|last3=Marchlinski|first3=F|last4=Saoudi|first4=N|title=Atrial flutter: more than just one of a kind|journal=European Heart Journal|date=September 2015|volume=36|issue=35|pages=2356–63|doi=10.1093/eurheartj/ehv118|pmid=25838435|doi-access=free}}</ref> The overall incidence of AFL has been estimated at 88 cases per 100,000 [[person-year]]s. The incidence of AFL is significantly lower (~5 cases/100,000 person-years) in those younger than age 50 and is far more common (587 cases/100,000 person-years) in those over 80 years of age.<ref name="Bun2015"/>