Editing Beta sheet (section)

{{short description|Protein structural motif}}
[[File:Animated Beta sheet.gif|thumb|Three-dimensional structure<ref>{{Cite web | url=https://proteopedia.org/w/Beta_sheet |title = Animated GIF made by adapting a 3D model from ''Beta sheet - Proteopedia, Life in 3D'' |website=proteopedia.org}}</ref> of parts of a beta sheet in [[green fluorescent protein]]]]
{{Alpha beta structure}}
The '''beta sheet''' ('''β-sheet''', also '''β-pleated sheet''') is a common [[structural motif|motif]] of the regular [[protein secondary structure]]. Beta sheets consist of '''beta strands''' ('''β-strands''') connected laterally by at least two or three [[backbone chain|backbone]] [[hydrogen bond]]s, forming a generally twisted, pleated sheet. A β-strand is a stretch of [[peptide|polypeptide]] chain typically 3 to 10 [[amino acid]]s long with backbone in an extended [[conformational isomerism|conformation]]. The supramolecular association of β-sheets has been implicated in the formation of the [[Amyloid fibril|fibrils]] and [[Amyloid plaques|protein aggregates]] observed in [[amyloidosis]],  [[Alzheimer's disease]] and other [[Proteinopathy|proteinopathies]].