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CASP
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{{Short description|Protein structure prediction challenge}} {{Other}} [[File:Target3dsmRib 354predictedModels CASP8.jpg|thumb|right|250px|A target structure (ribbons) and 354 template-based predictions superimposed (gray Calpha backbones); from CASP8]] '''Critical Assessment of Structure Prediction''' ('''CASP'''), sometimes called '''Critical Assessment of Protein Structure Prediction''', is a community-wide, worldwide experiment for [[protein structure prediction]] taking place every two years since 1994.<ref>{{Cite web |url=https://predictioncenter.org/casp15/index.cgi |title=Home - CASP15 |website=predictioncenter.org |access-date=2022-12-14}}</ref><ref>{{cite journal |vauthors=Moult J, Pedersen JT, Judson R, Fidelis K |title=A large-scale experiment to assess protein structure prediction methods |journal=Proteins |volume=23 |issue=3 |pages=ii-v |date=November 1995 |pmid=8710822 |doi=10.1002/prot.340230303 |url=https://zenodo.org/record/1229334 |s2cid=11216440}}</ref> CASP provides research groups with an opportunity to objectively test their structure prediction methods and delivers an independent assessment of the state of the art in protein structure modeling to the research community and software users. Even though the primary goal of CASP is to help advance the methods of identifying [[protein]] three-dimensional structure from its amino acid sequence many view the experiment more as a "world championship" in this field of science. More than 100 research groups from all over the world participate in CASP on a regular basis and it is not uncommon for entire groups to suspend their other research for months while they focus on getting their servers ready for the experiment and on performing the detailed predictions.
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