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CATH database
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{{Infobox biodatabase |title = CATH |logo = [[file:CATH - Protein Structure Classification Database.png|200px]] |description =Protein Structure Classification |scope = |organism = |center =[[University College London]] |laboratory = Institute of Structural and Molecular Biology |author = |citation = Dawson et al. (2016) <ref name=Cathv4.1>{{cite journal | vauthors = Dawson NL, Lewis TE, Das S, Lees JG, Lee D, Ashford P, Orengo CA, Sillitoe I | display-authors = 6 | title = CATH: an expanded resource to predict protein function through structure and sequence | journal = Nucleic Acids Research | volume = 45 | issue = D1 | pages = D289βD295 | date = January 2017 | pmid = 27899584 | pmc = 5210570 | doi = 10.1093/nar/gkw1098 }}</ref> |released = 1997 |standard = |format = |url = {{URL|cathdb.info}} |download = {{URL|cathdb.info/download}} |webservice = |sql = |sparql = |webapp = |standalone = |license = |versioning = |frequency = CATH-B is released daily. Official releases are approximately annual. |curation = |bookmark = |version = 4.3 }} {{Redirect|CATH|other uses|Cath (disambiguation){{!}}Cath}} [[Image:CATH hierarchy.png|thumb|262px|Schematic representation of the three top levels of the CATH classification scheme.<ref name="Orengo_1997">{{cite journal | vauthors = Orengo CA, Michie AD, Jones S, Jones DT, Swindells MB, Thornton JM | title = CATH--a hierarchic classification of protein domain structures | journal = Structure | location = London, England | volume = 5 | issue = 8 | pages = 1093β108 | date = August 1997 | pmid = 9309224 | doi = 10.1016/s0969-2126(97)00260-8 | doi-access = free }}</ref>]] The '''CATH Protein Structure Classification database''' is a free, publicly available online resource that provides information on the evolutionary relationships of [[protein domain]]s. It was created in the mid-1990s by Professor [[Christine Orengo]] and colleagues including [[Janet Thornton]] and [[David Tudor Jones|David Jones]],<ref name="Orengo_1997" /> and continues to be developed by the Orengo group at [[University College London]]. CATH shares many broad features with the [[Structural Classification of Proteins|SCOP]] resource, however there are also many areas in which the detailed classification differs greatly.<ref>{{cite web|url=http://www.cathdb.info |title=CATH: Protein Structure Classification Database at UCL |website=Cathdb.info |access-date=2017-03-09}}</ref><ref>{{cite web|url=http://www.cathdb.info/wiki/doku/?id=tutorials:index |title=CATH |website=Cathdb.info |access-date=2017-03-09}}</ref><ref>{{cite web|url=https://twitter.com/CATHDatabase |title=CATH Database (@CATHDatabase) |publisher=[[Twitter]] |access-date=2017-03-09}}</ref><ref name= Pearl2003>{{cite journal | vauthors = Pearl FM, Bennett CF, Bray JE, Harrison AP, Martin N, Shepherd A, Sillitoe I, Thornton J, Orengo CA | display-authors = 6 | title = The CATH database: an extended protein family resource for structural and functional genomics | journal = Nucleic Acids Research | volume = 31 | issue = 1 | pages = 452β455 | date = January 2003 | pmid = 12520050 | pmc = 165509 | doi = 10.1093/nar/gkg062 }}</ref>
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