Editing CDNA library (section)

{{Short description|Type of DNA library}}
{{lowercase|title=cDNA Library}}
{{More references|date=May 2008}}
A '''cDNA library''' is a combination of cloned cDNA ([[complementary DNA]]) fragments inserted into a collection of host cells, which constitute some portion of the [[transcriptome]] of the organism and are stored as a "[[DNA library|library]]". cDNA is produced from fully transcribed [[mRNA]] found in the [[Cell nucleus|nucleus]] and therefore contains only the expressed genes of an organism. Similarly, tissue-specific cDNA libraries can be produced. In [[eukaryotic]] cells the mature mRNA is already [[RNA splicing|spliced]], hence the cDNA produced lacks [[introns]] and can be readily expressed in a bacterial cell. While information in cDNA libraries is a powerful and useful tool since gene products are easily identified, the libraries lack information about [[enhancers]], [[introns]], and other regulatory elements found in a [[genomic library|genomic DNA library]].<ref>{{Cite web |title=cDNA Libraries - an overview {{!}} ScienceDirect Topics |url=https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/cdna-libraries#:~:text=A%20cDNA%20library%20is%20a,stands%20for%20'complementary'). |access-date=2024-02-19 |website=www.sciencedirect.com}}</ref><ref>{{Cite web |title=cDNA Library Overview and Applications - Creative Biogene |url=https://www.creative-biogene.com/support/cdna-library-overview-and-applications.html |access-date=2024-10-17 |website=www.creative-biogene.com}}</ref>