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Coding region
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{{short description|Portion of gene's sequence which codes for protein}} The '''coding region''' of a [[gene]], also known as the '''coding DNA sequence''' ('''CDS'''), is the portion of a gene's [[DNA]] or [[RNA]] that codes for a [[protein]].<ref name=":12">{{cite web|url=http://genome.wellcome.ac.uk/doc_WTD020755.html|title=Gene Structure|last=Twyman|first=Richard|date=1 August 2003|publisher=The Wellcome Trust|url-status=dead|archive-url=https://web.archive.org/web/20070328214808/http://genome.wellcome.ac.uk/doc_WTD020755.html|archive-date=28 March 2007|access-date=6 April 2003}}</ref> Studying the length, composition, regulation, splicing, structures, and functions of coding regions compared to non-coding regions over different species and time periods can provide a significant amount of important information regarding gene organization and evolution of [[prokaryote]]s and [[eukaryote]]s.<ref>{{Cite journal | vauthors = Höglund M, Säll T, Röhme D |date=February 1990|title=On the origin of coding sequences from random open reading frames|journal=Journal of Molecular Evolution|volume=30|issue=2|pages=104–108|doi=10.1007/bf02099936|issn=0022-2844|bibcode=1990JMolE..30..104H|s2cid=5978109}}</ref> This can further assist in mapping the [[Human Genome Project|human genome]] and developing gene therapy.<ref>{{cite journal | vauthors = Sakharkar MK, Chow VT, Kangueane P | title = Distributions of exons and introns in the human genome | journal = In Silico Biology | volume = 4 | issue = 4 | pages = 387–93 | date = 2004 | doi = 10.3233/ISB-00142 | pmid = 15217358 }}</ref>
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