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Cold Spring Harbor Laboratory
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{{Short description|Private, non-profit research institution in US}} {{Use American English|date=January 2025}} {{Use mdy dates|date=August 2023}} {{Infobox institute | name = Cold Spring Harbor Laboratory | image = Cold Spring Harbor Laboratory logo.png | image_name = | image_size = 250px | image_alt = | caption = The logo of Cold Spring Harbor Laboratory | latin_name = | established = {{start date and age|1890}} | president = [[Bruce Stillman]] | chairman = | head_label = | head = | staff = 1,200 | budget = $150 million | endowment = | debt = | members = | location = 1 Bungtown Road | city = [[Laurel Hollow, New York|Laurel Hollow]] | state = [[New York (state)|New York]] | province = | country = [[United States]] | coor = | address = | website = {{URL|http://www.cshl.edu/}} | footnotes = {{Infobox NRHP | name = Cold Spring Harbor Laboratory Historic District | embed = yes | nrhp_type = hd | nocat = yes | image = | caption = | location = Jct. of NY 25A and Bungtown Rd., [[Laurel Hollow, New York]] | coordinates = {{coord|40|51|30|N|73|28|00|W|display=inline,title}} | locmapin = New York#USA | mapframe = yes | built = | architect = Multiple | architecture = Multiple | added = March 30, 1994 | area = {{convert|110|acre}} | refnum = 94000198<ref name="nris">{{NRISref|version=2009a}}</ref> }} }} [[File:Cold Spring Harbor Laboratory.jpg|thumbnail|Cold Spring Harbor Laboratory]] '''Cold Spring Harbor Laboratory''' ('''CSHL''') is a private, [[non-profit organization|non-profit institution]] with [[research]] programs focusing on cancer, [[neuroscience]], [[botany]], [[genomics]], and [[quantitative biology]].<ref>{{Cite web |url=http://www.cshl.edu/Annual-Reports/2012-annual-report |title=Cold Spring Harbor Laboratory | 2012 Annual Report |access-date=2014-03-14 |archive-url=https://web.archive.org/web/20140314235223/http://www.cshl.edu/Annual-Reports/2012-annual-report |archive-date=2014-03-14 |url-status=dead }}</ref> It is located in [[Laurel Hollow, New York|Laurel Hollow]], [[New York (state)|New York]], in [[Nassau County, New York|Nassau County]], on [[Long Island]]. It is one of 68 institutions supported by the [[NCI-designated Cancer Center|Cancer Centers Program]] of the U.S. [[National Cancer Institute]] (NCI) and has been an NCI-designated Cancer Center since 1987.<ref>{{Cite web |url=http://cancercenters.cancer.gov/cancer_centers/index.html |title=Cancer Centers Program - Cancer Centers |access-date=2014-03-14 |archive-url=https://web.archive.org/web/20140223100054/http://cancercenters.cancer.gov/cancer_centers/index.html |archive-date=2014-02-23 |url-status=dead }}</ref> The Laboratory is one of a handful of institutions that played a central role in the development of [[molecular genetics]] and [[molecular biology]].<ref>Horace Freedland Judson, ''The Eighth Day of Creation: The Makers of the Revolution in Biology'' (Simon & Schuster, 1979), esp. pp. 65-69; also: 44-46; 53; 57-58; 62; 70; 82; 185; 232; 239; 247; 273; 321; 368; 392; 454; 458-59; 572-73.</ref> It has been home to eight scientists who have been awarded the [[Nobel Prize in Physiology or Medicine]]. CSHL is ranked among the leading [[basic research]] institutions in molecular biology and genetics, with Thomson Reuters ranking it first in the world.<ref>See Thomson Reuters Essential Science Indicators, [http://archive.sciencewatch.com/dr/sci/08/may25-08_4/]. The ranking is based on average citation frequency of faculty research papers published between January 2002 and December 2012, including 96.94 citations for each CSHL paper on average.</ref> CSHL was also ranked first in research output worldwide by ''Nature''.<ref>{{Cite journal|date=2019-06-19|title=Top 10 academic institutions in 2018: normalized|url=http://www.nature.com/articles/d41586-019-01924-x|journal=Nature|language=EN|doi=10.1038/d41586-019-01924-x|s2cid=241263716|url-access=subscription}}</ref> The Laboratory is led by [[Bruce Stillman]], a biochemist and cancer researcher. Since its inception in 1890, the institution's campus on the [[North Shore (Long Island)|North Shore]] of [[Long Island]] has also been a center of biology education. Current CSHL educational programs serve professional scientists, doctoral students in biology, teachers of biology in the Kβ12 system, and students from the elementary grades through high school. In the past 10 years, CSHL conferences & courses have drawn over 81,000 scientists and students to the main campus.<ref name="cshl.edu">{{cite web|url=http://www.cshl.edu/About-Us/Facts-Figures|title=CSHL Facts & Figures - About Us|author=WebServices|access-date=2014-03-14|archive-url=https://web.archive.org/web/20140322050319/https://www.cshl.edu/About-Us/Facts-Figures|archive-date=2014-03-22|url-status=dead}}</ref> For this reason, many scientists consider CSHL a "crossroads of biological science."<ref>Examples include: Francis Collins, M.D., Ph.D., current director of the U.S. National Institutes of Health: [http://library.cshl.edu/oralhistory/interview/genome-research/competition-science/competition-human-genome-project-public-vs-private/]; Nobel laureate Sydney Brenner: [http://library.cshl.edu/oralhistory/interview/cshl/special-aspects/cold-spring-harbor-laboratory-center-science/]; Nobel laureate Eric Kandel, M.D., referring to the institutional setting of CSHL's graduate school: [http://www.cshl.edu/Archive/watson-school-of-biological-sciences-culminates-commencement-weekend-conferring-degrees-on-its-fifth-graduating-class]; See also: R. Sanders Williams, "Sputnik, Slime Molds, and Botticelli in the Making of a Physician-Scientist," in David A. Schwartz, ed., Medicine, Science and Dreams: The Making of Physician-Scientists (Springer, 2010, p. 103.)</ref> Since 2009 CSHL has partnered with the [[Suzhou Industrial Park]] in [[Suzhou, Jiangsu|Suzhou]], China to create '''Cold Spring Harbor Asia''' which annually draws some 3,000 scientists to its meetings and courses.<ref>{{cite web|url=http://www.csh-asia.org/overview.html|title=CSH Asia Overview|website=www.csh-asia.org}}</ref> The [[Cold Spring Harbor Laboratory School of Biological Sciences]], formerly the Watson School of Biological Sciences, was founded in 1999.<ref>{{cite web |title=CSHL trustees vote on future of graduate school |url=https://www.cshl.edu/cshl-trustees-vote-on-future-of-graduate-school/ |website=Cold Spring Harbor Laboratory |access-date=4 July 2020 |date=3 July 2020}}</ref> In 2015, CSHL announced a strategic affiliation with the nearby [[Northwell Health]] to advance cancer therapeutics research, develop a new clinical cancer research unit at Northwell Health in [[Lake Success, New York|Lake Success]], NY, to support early-phase clinical studies of new cancer therapies, and recruit and train more clinician-scientists in oncology.<ref>{{cite web|url=http://www.cshl.edu/news-and-features/cold-spring-harbor-laboratory-and-north-shore-lij-announce-strategic-affiliation-to-accelerate-benefits-of-cancer-research-to-patients.html|title=CSHL Cold Spring Harbor Laboratory and North Shore-LIJ announce strategic affiliation to accelerate benefits of cancer research to patients - News & Features|author=Dagnia Zeidlickis|access-date=2015-10-16|archive-url=https://web.archive.org/web/20151031104416/http://www.cshl.edu/news-and-features/cold-spring-harbor-laboratory-and-north-shore-lij-announce-strategic-affiliation-to-accelerate-benefits-of-cancer-research-to-patients.html|archive-date=2015-10-31|url-status=dead}}</ref> CSHL hosts [[bioRxiv]], a preprint repository for publications in the life sciences.
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