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Cyclopia
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{{short description|Failure of the eye orbits to separate in two during embryonic development}} {{Use dmy dates|date=January 2025}}{{about|the congenital disorder}} {{Infobox medical condition (new) | name = Cyclopia | synonyms = Cyclocephaly, synophthalmia | image = Cyclopia fetuses.jpg | caption = Fetuses with cyclopia | pronounce = | field = [[Medical genetics]] | symptoms = | complications = | onset = During embryonic development | duration = Lifelong | types = | causes = | risks = | diagnosis = | differential = | prevention = | treatment = | medication = | prognosis = Invariably Fatal | frequency = 1 in 100,000 births | deaths = }} '''Cyclopia''' (named after the Greek mythology characters [[cyclopes]]), also known as '''alobar holoprosencephaly''', is the most extreme form of [[holoprosencephaly]] and is a [[congenital disorder]] (birth defect) characterized by the failure of the embryonic [[prosencephalon]] to properly divide the [[Orbit (anatomy)|orbits]] of the eye into two cavities. Its incidence is 1 in 16,000 in born animals and 1 in 200 in [[miscarriage|miscarried fetuses]].<ref>''Taber's Cyclopedic Medical Dictionary'', {{ISBN|0-8036-0654-0}}</ref><ref>[[Armand Marie Leroi|Leroi, Armand Marie]] ''Mutants: On Genetic Variety and the Human Body'', p.73. {{ISBN|978-0142004821}}</ref>
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