Editing Cytochrome c (section)

{{short description|Protein-coding gene in the species Homo sapiens}}
{{cs1 config|name-list-style=vanc|display-authors=sainivas}}
{{Infobox gene}}
[[File:Cytochrome c image 2.png|thumb|Heme prosthetic group of cytochrome c, consisting of a rigid porphyrin ring coordinated with an iron atom.]]
The '''cytochrome complex''', or '''cyt c''', is a small [[hemeprotein]] found loosely associated with the [[inner mitochondrial membrane|inner membrane]] of the [[mitochondrion]] where it plays a critical role in [[cellular respiration]]. 
It [[Electron transport chain|transfers electrons]] between [[Coenzyme Q - cytochrome c reductase|Complexes III]] (Coenzyme Q – Cyt c reductase) and [[cytochrome c oxidase|IV]] (Cyt c oxidase). Cytochrome c is highly [[Water soluble|water-soluble]], unlike other [[cytochrome]]s. It is capable of undergoing [[oxidation]] and [[redox|reduction]] as its [[iron]] atom converts between the [[ferrous]] and [[ferric]] forms, but does not bind [[oxygen]].  It also plays a major role in cell [[apoptosis]]. In humans, cytochrome c is encoded by the ''CYCS'' [[gene]].<ref name="entrez">{{Cite web |title=Entrez Gene: cytochrome c |url=https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54205}}</ref><ref name="pmid11790791">{{Cite journal |vauthors=Tafani M, Karpinich NO, Hurster KA, Pastorino JG, Schneider T, Russo MA, Farber JL |date=March 2002 |title=Cytochrome c release upon Fas receptor activation depends on translocation of full-length bid and the induction of the mitochondrial permeability transition |journal=[[The Journal of Biological Chemistry]] |volume=277 |issue=12 |pages=10073–82 |doi=10.1074/jbc.M111350200 |pmid=11790791 |doi-access=free}}</ref>