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Enterotoxin
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{{Short description|Toxin from a microorganism affecting the intestines}} {{Infobox protein family | Symbol = Stap_Strp_tox_C | Name = Staph/Strep enterotoxin, C terminal | image = PDB 1uns EBI.jpg | width = | caption = identification of a secondary zinc-binding site in staphylococcal enterotoxin c2: implications for superantigen recognition | Pfam = PF02876 | Pfam_clan = CL0386 | InterPro = IPR006123 | SMART = | PROSITE = PDOC00250 | MEROPS = | SCOP = 1se3 | TCDB = | OPM family = 364 | OPM protein = 1dyq | CAZy = | CDD = }} An '''enterotoxin''' is a [[protein]] [[exotoxin]] released by a [[microorganism]] that targets the [[intestines]].<ref>{{DorlandsDict|three/000035767|enterotoxin}}</ref> They can be chromosomally or plasmid encoded.<ref>Carlton Gyles, Magdalene So, Stanley Falkow, Journal of Infectious Diseases (1974) 130 (1): 40-49.</ref> They are heat [[Lability#Biology|labile]] (> 60 Β°C), of low molecular weight and water-soluble. Enterotoxins are frequently [[cytotoxic]] and kill cells by altering the apical membrane [[Semipermeable membrane|permeability]] of the mucosal ([[epithelial]]) cells of the intestinal wall. They are mostly [[pore-forming toxin]]s (mostly chloride pores), secreted by bacteria, that assemble to form pores in [[cell membranes]]. This causes the cells to die.
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