Editing Factor XII (section)

{{Short description|Mammalian protein involved in blood clotting}}
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'''Coagulation factor XII''', also known as  '''Hageman factor''', is a [[plasma protein]] involved in [[coagulation]]. It is the [[zymogen]] form of factor XIIa ({{EC number|3.4.21.38}}), an [[enzyme]] of the [[serine protease]] (or serine endopeptidase) class.  In humans, factor XII is encoded by ''F12'' [[gene]].<ref name="pmid2888762">{{cite journal | vauthors = Cool DE, MacGillivray RT | title = Characterization of the human blood coagulation factor XII gene. Intron/exon gene organization and analysis of the 5'-flanking region | journal = The Journal of Biological Chemistry | volume = 262 | issue = 28 | pages = 13662–13673 | date = October 1987 | pmid = 2888762 | doi = 10.1016/S0021-9258(19)76478-3 | doi-access = free }}</ref>