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Gene duplication
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{{Short description|Duplication of a gene sequence within a genome}} '''Gene duplication''' (or '''chromosomal duplication''' or ''' gene amplification''') is a major mechanism through which new genetic material is generated during [[molecular evolution]]. It can be defined as any duplication of a region of [[DNA]] that contains a [[gene]]. Gene duplications can arise as products of several types of errors in [[DNA replication]] and [[DNA repair|repair]] machinery as well as through fortuitous capture by selfish genetic elements. Common sources of gene duplications include [[ectopic recombination]], [[retrotransposon|retrotransposition]] event, [[aneuploidy]], [[polyploidy]], and [[replication slippage]].<ref name="Zhang_2003">{{cite journal |author=Zhang J |title=Evolution by gene duplication: an update |journal=Trends in Ecology & Evolution |volume=18 |issue=6 |pages=292β8 |year=2003 |doi=10.1016/S0169-5347(03)00033-8 |url=http://www.umich.edu/~zhanglab/publications/2003/Zhang_2003_TIG_18_292.pdf }}</ref>
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