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Hyperphosphatemia
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{{Short description|Excess phosphate in the blood}} {{cs1 config|name-list-style=vanc}} {{distinguish|text=[[hypophosphatemia]] (low phosphate levels in the blood)}} {{Infobox medical condition (new) | name = Hyperphosphatemia | synonyms = | image = Phosphate Group.svg | caption = Phosphate group chemical structure | pronounce = | field = [[Endocrinology]], [[nephrology]] | symptoms = None, calcium deposits, muscle spasms<ref name=Mer2018/> | complications = [[Low blood calcium]]<ref name=Mer2018/> | onset = | duration = | types = | causes = [[Kidney failure]], [[pseudohypoparathyroidism]], [[hypoparathyroidism]], [[diabetic ketoacidosis]], [[tumor lysis syndrome]], [[rhabdomyolysis]]<ref name=Mer2018/> | risks = | diagnosis = Blood phosphate > 1.46 mmol/L (4.5 mg/dL)<ref name=Mer2018/> | differential = [[dyslipidemia|High blood lipids]], [[hyperproteinemia|high blood protein]], [[hyperbilirubinemia|high blood bilirubin]]<ref name=Mer2018/> | prevention = | treatment = Decreasing intake, [[calcium carbonate]]<ref name=Mer2018/> | medication = | prognosis = | frequency = Unclear<ref name=Ron2008/> | deaths = }} <!-- Definition and symptoms --> '''Hyperphosphatemia''' is an [[electrolyte disorder]] in which there is an elevated level of [[phosphate]] in the [[blood]].<ref name=Mer2018/> Most people have no symptoms while others develop [[ectopic calcification|calcium deposits]] in the soft tissue.<ref name=Mer2018/> The disorder is often accompanied by [[low calcium]] blood levels, which can result in muscle spasms.<ref name=Mer2018>{{cite web |title=Hyperphosphatemia |url=https://www.merckmanuals.com/professional/endocrine-and-metabolic-disorders/electrolyte-disorders/hyperphosphatemia |website=Merck Manuals Professional Edition |access-date=27 October 2018}}</ref> <!-- Cause and diagnosis --> Causes include [[kidney failure]], [[pseudohypoparathyroidism]], [[hypoparathyroidism]], [[diabetic ketoacidosis]], [[tumor lysis syndrome]], and [[rhabdomyolysis]].<ref name=Mer2018/> Diagnosis is generally based on a blood phosphate level exceeding 1.46 mmol/L (4.5 mg/dL).<ref name=Mer2018/> Levels may appear falsely elevated with [[dyslipidemia|high blood lipid levels]], [[hyperproteinemia|high blood protein levels]], or [[hyperbilirubinemia|high blood bilirubin levels]].<ref name=Mer2018/> <!-- Treatment and epidemiology --> Treatment may include a phosphate low diet and [[antacids]] like [[calcium carbonate]] that bind phosphate.<ref name=Mer2018/> Occasionally, intravenous [[normal saline]] or [[kidney dialysis]] may be used.<ref name=Mer2018/> How commonly it occurs is unclear.<ref name=Ron2008>{{cite book |last1=Ronco |first1=Claudio |last2=Bellomo |first2=Rinaldo |last3=Kellum |first3=John A. |title=SPEC - Critical Care Nephrology Expert Consult (Book Program) Pincard |date=2008 |publisher=Elsevier Health Sciences |isbn=978-1437711110 |page=533 |url=https://books.google.com/books?id=MdgvSwnlgRgC&pg=PA533 |language=en}}</ref>
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