Editing Hypertrophy (section)

{{short description|Increase in the volume of an organ or tissue due to the enlargement of its component cells}}
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| name          = Hypertrophy
| image         = Hyperplasia vs Hypertrophy.svg
| caption       = Hypertrophy results from an increase in cell size, whereas [[hyperplasia]] stems from an increase in cell number.|
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'''Hypertrophy''' is the increase in the volume of an organ or tissue due to the enlargement of its component [[Cell (biology)|cells]].<ref name="Muscle Hypertrophy">{{cite web|last1=Hernandez|first1=Richard|last2=Kravitz|first2=Len|title=Skeletal muscle hypertrophy|url=https://www.unm.edu/~lkravitz/Article%20folder/hypertrophy.html|website=www.unm.edu}}</ref> It is distinguished from [[hyperplasia]], in which the cells remain approximately the same size but increase in number.<ref>{{Cite web|title=Hyperplasia: MedlinePlus Medical Encyclopedia|url=https://medlineplus.gov/ency/article/003441.htm|access-date=2023-02-19|website=medlineplus.gov|language=en}}</ref> Although hypertrophy and hyperplasia are two distinct processes, they frequently occur together, such as in the case of the [[hormone|hormonally]] induced proliferation and enlargement of the cells of the [[uterus]] during [[pregnancy]].

'''Eccentric hypertrophy''' is a type of hypertrophy where the walls and chamber of a hollow organ undergo growth in which the overall size and volume are enlarged. It is applied especially to the [[left ventricle]] of heart.<ref name=Kusumoto2004 >{{citation | last=Kusumoto | first=F. M. | year=2004 | title=Cardiovascular Pathophysiology | publisher=Hayes Barton Press | isbn=978-1-59377-189-8 | url=https://books.google.com/books?id=FHT_w_gUeK4C&q=Eccentric+hypertrophy&pg=PA22 | pages=20–22 }}{{Dead link|date=August 2024 |bot=InternetArchiveBot |fix-attempted=yes }}</ref> [[Sarcomere]]s are added in series, as for example in [[dilated cardiomyopathy]] (in contrast to [[hypertrophic cardiomyopathy]], a type of [[concentric hypertrophy]], where sarcomeres are added in parallel).