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International HapMap Project
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{{Short description|Project that developed a haplotype map of the human genome}} {{primary sources|date=October 2012}} The '''International HapMap Project''' was an organization that aimed to develop a [[haplotype]] [[map]] ('''HapMap''') of the [[human genome]], to describe the common patterns of human [[genetic variability|genetic variation]]. HapMap is used to find genetic variants affecting health, disease and responses to drugs and environmental factors. The information produced by the project is made freely available for research. The International HapMap Project is a collaboration among researchers at academic centers, non-profit biomedical research groups and private companies in [[Canada]], [[China]] (including [[Hong Kong]]), [[Japan]], [[Nigeria]], the [[United Kingdom]], and the [[United States]]. It officially started with a meeting on October 27 to 29, 2002, and was expected to take about three years. It comprises three phases; the complete data obtained in Phase I were published on 27 October 2005.<ref>{{Cite journal|last1=Altshuler|first1=David|last2=Donnelly|first2=Peter|last3=The International HapMap Consortium|date=October 2005|title=A haplotype map of the human genome|journal=Nature|language=en|volume=437|issue=7063|pages=1299β1320|doi=10.1038/nature04226|pmid=16255080|pmc=1880871|bibcode=2005Natur.437.1299T|issn=1476-4687|doi-access=free}}</ref> The analysis of the Phase II dataset was published in October 2007.<ref>{{Cite journal|last1=Frazer|first1=Kelly A.|last2=Ballinger|first2=Dennis G.|last3=Cox|first3=David R.|last4=Hinds|first4=David A.|last5=Stuve|first5=Laura L.|last6=Gibbs|first6=Richard A.|last7=Belmont|first7=John W.|last8=Boudreau|first8=Andrew|last9=Hardenbol|first9=Paul|last10=Leal|first10=Suzanne M.|last11=Pasternak|first11=Shiran|date=October 2007|title=A second generation human haplotype map of over 3.1 million SNPs|url= |journal=Nature|language=en|volume=449|issue=7164|pages=851β861|doi=10.1038/nature06258|pmid=17943122|pmc=2689609|bibcode=2007Natur.449..851F|issn=1476-4687|hdl=2027.42/62863|hdl-access=free}}</ref> The Phase III dataset was released in spring 2009 and the publication presenting the final results published in September 2010.<ref>{{Cite journal|last1=Altshuler|first1=David M.|last2=Gibbs|first2=Richard A.|last3=Peltonen|first3=Leena|last4=Altshuler|first4=David M.|last5=Gibbs|first5=Richard A.|last6=Peltonen|first6=Leena|last7=Dermitzakis|first7=Emmanouil|last8=Schaffner|first8=Stephen F.|last9=Yu|first9=Fuli|last10=Peltonen|first10=Leena|last11=Dermitzakis|first11=Emmanouil|date=September 2010|title=Integrating common and rare genetic variation in diverse human populations|url= |journal=Nature|language=en|volume=467|issue=7311|pages=52β58|doi=10.1038/nature09298|pmid=20811451|issn=1476-4687|pmc=3173859|bibcode=2010Natur.467...52T}}</ref>
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