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Lateral geniculate nucleus
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{{short description|Component of the visual system in the brain's thalamus}} {{Redirect|LGN}} {{Infobox brain | Name = Lateral geniculate nucleus | Latin = corpus geniculatum laterale | Image = Gray719.png | Caption = [[Hindbrain|Hind-]] and [[mid-brain]]s; postero-lateral view. (Lateral geniculate body visible near top.) | Image2 = | Caption2 = | IsPartOf = [[Thalamus]] | System = [[Visual system|Visual]] | Components = | Artery = [[Anterior choroidal artery|Anterior choroidal]] and [[Posterior cerebral artery|Posterior cerebral]] | Vein = [[Terminal vein]] | Acronym = LGN }} In [[neuroanatomy]], the '''lateral geniculate nucleus''' ('''LGN'''; also called the '''lateral geniculate body''' or '''lateral geniculate complex''') is a structure in the [[thalamus]] and a key component of the mammalian [[visual pathway]]. It is a small, ovoid, [[Anatomical terms of location#Dorsal_and_ventral|ventral]] projection of the thalamus where the thalamus connects with the [[optic nerve]]. There are two LGNs, one on the left and another on the right side of the thalamus. In humans, both LGNs have six layers of [[neuron]]s ([[grey matter]]) alternating with optic fibers ([[white matter]]). The LGN receives information directly from the ascending [[retinal ganglion cell]]s via the optic tract and from the [[reticular activating system]]. Neurons of the LGN send their axons through the [[optic radiation]], a direct pathway to the [[primary visual cortex]]. In addition, the LGN receives many strong feedback connections from the primary [[visual cortex]].<ref name=Cudeiro2006>{{cite journal|last=Cudeiro|first=Javier|author2=Sillito, Adam M. |title=Looking back: corticothalamic feedback and early visual processing|journal=Trends in Neurosciences|year=2006|pages=298β306|volume=29|issue=6|pmid=16712965|doi=10.1016/j.tins.2006.05.002|citeseerx=10.1.1.328.4248|s2cid=6301290}}</ref> In [[humans]] as well as other [[mammals]], the two strongest pathways linking the eye to the brain are those projecting to the dorsal part of the LGN in the thalamus, and to the [[superior colliculus]].<ref>Goodale, M. & Milner, D. (2004)''Sight unseen.''Oxford University Press, Inc.: New York.</ref>
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