Editing Leydig cell (section)

{{Short description|Androgen-producing cell adjacent to the seminiferous tubules of the testicle}}
{{Infobox cell
| Name        = Leydig cell
| Width       =
| Image       = Leydig cells - very high mag.jpg
| Caption     = [[Micrograph]] showing a cluster of Leydig cells (center of image). [[H&E stain]].
| Image2      = Testicle-histology-boar-2.jpg
| Caption2    = Histological section through testicular [[parenchyma]] of a [[boar]]. 1 Lumen of convoluted part of the seminiferous tubules, 2 [[spermatid]]s, 3 [[spermatocyte]]s, 4 [[spermatogonium|spermatogonia]], 5 [[Sertoli cell]], 6 [[myofibroblast]]s, 7 Leydig cells, 8 [[capillary|capillaries]]
| Precursor   = 
| System      = 
| Artery      = 
| Vein        = 
| Nerve       = 
| Lymph       = 
}}
'''Leydig cells''', also known as '''interstitial cells of the testes''' and '''interstitial cells of Leydig''', are found adjacent to the [[seminiferous tubules]] in the [[testes|testicle]] and produce [[testosterone]] in the presence of [[luteinizing hormone]] (LH).<ref name="Chabner">{{Cite book|last=Chabner|first=Davi-Ellen|title=The Language of Medicine - E-Book|date=2016|publisher=Elsevier Health Sciences|isbn=978-0-32-337083-7|page=316|url=https://books.google.com/books?id=Ih6KCwAAQBAJ&pg=PA316}}</ref><ref name="Johnson">{{Cite book|last=Johnson|first=Martin H.|title=Essential Reproduction|date=2018|publisher=John Wiley & Sons|isbn=978-1-11-924645-9|page=131|url=https://books.google.com/books?id=3qJGDwAAQBAJ&pg=PA131}}</ref> They are polyhedral in shape and have a large, prominent [[cell nucleus|nucleus]], an [[eosinophilic]] [[cytoplasm]], and numerous lipid-filled vesicles.<ref name="Zhou">{{Cite book|last1=Zhou|first1=Ming|last2=Netto|first2=George|last3=Epstein|first3=Jonathan I|title=Uropathology E-Book|date=2022|publisher=Elsevier Health Sciences|isbn=978-0-32-365396-1|page=428|url=https://books.google.com/books?id=nGxpEAAAQBAJ&pg=PA428}}</ref> Males have two types of leydig cells that appear in two distinct stages of development: the fetal type and the adult type.<ref name="OLC">{{cite journal |last1=Carrasco-Juan |first1=JL |last2=Álvarez-Argüelles Cabrera |first2=H |last3=Martín Corriente |first3=MC |last4=González-Gómez |first4=M |last5=Valladares Parrilla |first5=R |last6=Gutiérrez García |first6=R |last7=Díaz-Flores |first7=L |title=Ovarian Leydig cells (OLC): A histomorphological and immunohistochemical study. |journal=Histology and Histopathology |date=October 2017 |volume=32 |issue=10 |pages=1089–1097 |doi=10.14670/HH-11-876 |pmid=28127725}}</ref>