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{{Short description|American scientist and activist (1901–1994)}} {{Use mdy dates|date=July 2023|cs1-dates=y}} {{Use American English|date=April 2022}} {{Infobox scientist | image = File:Linus Pauling in the 1940s.jpg | caption = Pauling in the 1940s | honorific_suffix = {{post-nominals|country=GBR|size=100%|ForMemRS}} | birth_name = Linus Carl Pauling | birth_date = {{birth date|1901|2|28}} | birth_place = [[Portland, Oregon]], U.S. | nationality = <!-- use only when necessary per [[WP:INFONAT]] --> | death_date = {{nowrap|{{death date and age|1994|8|19|1901|2|28}}}} | death_place = [[Big Sur]], California, U.S. | spouse = {{marriage|[[Ava Helen Pauling|Ava Helen Miller]]|1923-06-17|1981-12-07|end=d.}} | children = 4 | field = {{ubl|[[Quantum chemistry]]|[[Biochemistry]]}} | education = {{ubl|[[Oregon State University]] ([[B. S.|BS]])|[[California Institute of Technology]] ([[PhD]])}} | work_institution = {{collapsible list|title={{nobold|''As faculty member''}} |[[California Institute of Technology|Caltech]] (1927–1963) |[[University of California, San Diego|UC San Diego]] (1967–1969) |[[Stanford University|Stanford]] (1969–1975) }} {{collapsible list|title={{nobold|''As fellow''}} |[[Cornell University]] (1937–1938) |[[University of Oxford]] (1948) |[[Center for the Study of Democratic Institutions]] (1963–1967) }} | doctoral_advisor = {{ubl|[[Roscoe G. Dickinson|Roscoe Dickinson]]|[[Richard C. Tolman|Richard Tolman]]<ref name="mathgene">{{MathGenealogy|id=113591}}</ref>}} | academic_advisors = {{ubl|[[Arnold Sommerfeld]]|[[Niels Bohr]]<ref name="Guggenheim">{{Cite web |title=A Guggenheim Fellow in Europe during the Golden Years of Physics (1926–1927) |url=http://scarc.library.oregonstate.edu/coll/pauling/chronology/page9.html |url-status=live |archive-url=https://web.archive.org/web/20211028235401/http://scarc.library.oregonstate.edu/coll/pauling/chronology/page9.html |archive-date=October 28, 2021 |access-date=May 27, 2015 |website=[[Oregon State University]] |language=en-US}}</ref>}} | doctoral_students = {{plainlist| *[[Jerry Donohue]] *[[Harvey Itano]] *[[Barclay Kamb]] *[[Martin Karplus]] *[[Leonard Lerman]] *[[William Lipscomb]]<ref name="mathgene" /> *[[Matthew Meselson]] *[[Kurt Mislow]] *[[Arthur Pardee]] *[[Robert E. Rundle]] *[[Edgar Bright Wilson]] }} | notable_students = ''Undergrads:'' {{plainlist | * [[Edwin McMillan]] }} ''Post-docs:'' {{plainlist | *[[Charles D. Coryell]] *[[Jack D. Dunitz]] *[[Sidney W. Fox]] *[[Walter Gordy]] *[[Edgar Heilbronner]] *[[Jan Ketelaar]] *[[Hans Kuhn (chemist)|Hans Kuhn]] *[[Leslie Orgel]] *[[Alexander Rich]] *[[Seymour Jonathan Singer]] }} | thesis_title = The Determination with X-Rays of the Structures of Crystals | thesis_year = 1925<ref name="paulingphd">{{Cite thesis |last=Pauling |first=Linus |title=The determination with x-rays of the structures of crystals |date=1925 |degree=PhD |publisher=[[California Institute of Technology]] |url=https://thesis.library.caltech.edu/1791/ |doi=10.7907/F7V6-4P98 |language=en |author-mask=4 |access-date=April 13, 2022}}</ref> | thesis_url = https://thesis.library.caltech.edu/1791 | known_for = {{collapsible list|title={{nobold|''See list''}}|{{ubl|item_style={{longitem}} |[[Alpha sheet]] |[[Ancestral sequence reconstruction]] |[[Pi backbonding|Backbonding]] |[[Beta sheet]] |[[Bond order]] |[[Breath gas analysis]] |[[Coiled coil]] |[[Corey-Pauling rules]] |[[CPK coloring]] |[[Crystal structure prediction]] |[[Electronegativity]] |Elucidating [[chemical bond]]s and [[molecular structure]]s |[[Geometrical frustration]] |[[Orbital hybridisation|Hybridisation theory]] |[[Hydrogen bond]]ing |[[Ice-type model]] |[[Linear combination of atomic orbitals]] |[[Molecular clock]] |[[Molecular medicine]] |[[Non-carbon nanotube]] |[[Orbital overlap]] |[[Cooperative binding#Pauling equation|Pauling equation]] |[[Pauling's rules]] |[[Pauling–Corey–Branson alpha helix]] |[[Pauling's principle of electroneutrality]] |[[Quantum chemistry]] |[[Quantum graph]] |[[Residual entropy]] |[[Resonance (chemistry)]] |[[Slater–Pauling rule]] |[[Space-filling model]] |[[Valence bond theory]] |[[Vitamin C megadosage]] |[[Xenic acid]] |Advocating [[nuclear disarmament]] }}}} | prizes = {{ubl|item_style={{longitem}} | [[ACS Award in Pure Chemistry]] (1931) | [[Irving Langmuir Award]] (1931) | [[Davy Medal]] (1947) | [[Nobel Prize in Chemistry]] (1954) | [[Nobel Peace Prize]] (1962) | [[Roebling Medal]] (1967) | [[Lenin Peace Prize]] (1968–1969) | [[National Medal of Science]] (1974) | [[Lomonosov Gold Medal]] (1977) | [[NAS Award in Chemical Sciences]] (1979) | [[Priestley Medal]] (1984) | [[Vannevar Bush Award]] (1989) }} | signature = Linus Pauling signature.svg | footnotes = The only person to win two unshared Nobel Prizes. }} '''Linus Carl Pauling''' {{Post-nominals|country=GBR|FRS}} ({{IPAc-en|ˈ|p|ɔː|l|ɪ|ŋ}} {{respell|PAW|ling}}; February 28, 1901{{snd}}August 19, 1994)<ref name="ChemNobel">{{Cite web |title=Linus Pauling: Facts |url=https://www.nobelprize.org/prizes/chemistry/1954/pauling/facts/ |url-status=live |archive-url=https://web.archive.org/web/20220404140945/https://www.nobelprize.org/prizes/chemistry/1954/pauling/facts/ |archive-date=April 4, 2022 |access-date=April 13, 2022 |website=Nobel Prize |language=en}}</ref> was an American [[chemist]], [[biochemist]], [[chemical engineer]], [[peace activist]], author, and educator. He published more than 1,200 papers and books, of which about 850 dealt with scientific topics.<ref name="VolumeI">{{Cite book |last=Pauling |first=Linus |title=Selected papers of Linus Pauling |date=1997 |publisher=[[World Scientific]] |isbn=978-981-02-2939-9 |editor-last=Pauling |editor-first=Linus Jr. |edition=Volume I |location=[[River Edge, New Jersey]] |page=xvii |author-mask=4}}</ref> ''[[New Scientist]]'' called him one of the 20 greatest scientists of all time.<ref name="Horgan">{{Cite magazine |last=Horgan |first=J |year=1993 |title=Profile: Linus C. Pauling – Stubbornly Ahead of His Time |magazine=[[Scientific American]] |volume=266 |issue=3 |pages=36–40 |bibcode=1993SciAm.266c..36H |doi=10.1038/scientificamerican0393-36}}</ref> For his scientific work, Pauling was awarded the [[Nobel Prize in Chemistry]] in 1954. For his peace activism, he was awarded the [[Nobel Peace Prize]] in 1962. He is one of five people to have [[Nobel Prize#Multiple laureates|won more than one Nobel Prize]] (the others being [[Marie Curie]], [[John Bardeen]], [[Frederick Sanger]], and [[Karl Barry Sharpless]]).<ref name="Nobel">{{Nobelprize|access-date=April 30, 2020}}</ref> Of these, he is the only person to have been awarded two unshared Nobel Prizes,<ref>{{Cite web |date=April 12, 2022 |orig-date=2009-10-05 |title=Nobel Prize Facts |url=https://www.nobelprize.org/nobel_prizes/facts/ |url-status=live |archive-url=https://web.archive.org/web/20170111161907/http://www.nobelprize.org/nobel_prizes/facts/ |archive-date=January 11, 2017|access-date=April 13, 2022 |website=Nobel Prize |language=en }}</ref> and one of two people to be awarded Nobel Prizes in different fields, the other being [[Marie Curie]].<ref name="Nobel" /> Pauling was one of the founders of the fields of [[quantum chemistry]] and [[molecular biology]].<ref name="natureobit">{{Cite journal |last=Rich |first=Alexander |author-link=Alexander Rich |year=1994 |title=Linus Pauling (1901–1994) |journal=[[Nature (journal)|Nature]] |volume=371 |issue=6495 |pages=285 |bibcode=1994Natur.371..285R |doi=10.1038/371285a0 |pmid=8090196 |doi-access=free |s2cid=8923975}}</ref> His contributions to the theory of the chemical bond include the concept of [[orbital hybridisation]] and the first accurate scale of [[electronegativity|electronegativities]] of the elements. Pauling also worked on the structures of biological molecules, and showed the importance of the [[alpha helix]] and [[beta sheet]] in [[protein secondary structure]]. Pauling's approach combined methods and results from [[X-ray crystallography]], [[molecular model]] building, and quantum chemistry. His discoveries inspired the work of [[Rosalind Franklin]], [[James Watson]], [[Francis Crick]], and [[Maurice Wilkins]] on the structure of [[DNA]], which in turn made it possible for geneticists to crack the DNA code of all organisms.<ref name="Contributions to DNA double-helix discovery">{{Cite book |last=Gribbin |first=John |title=The Scientists: A History of Science Told Through the Lives of Its Greatest Inventors |date=2004 |publisher=[[Random House]] |isbn=978-0-8129-6788-3 |location=New York City |pages=558–569 |language=en |ol=8020832M |author-link=John Gribbin}}</ref> In his later years, he promoted [[nuclear disarmament]], as well as [[orthomolecular medicine]], [[megavitamin therapy]],<ref name="isbn0-399-50764-7">{{Cite book |last=Stone |first=Irwin |author-link=Irwin Stone |url=https://archive.org/details/healingfactorvit0000ston |title=The healing factor: "vitamin C" against disease |date=1982 |publisher=Perigee Books |isbn=978-0-399-50764-9 |location=New York|language=en |oclc=10169988 |ol=9567597M |via=[[Internet Archive]]}}</ref> and [[dietary supplement]]s, especially [[ascorbic acid]] (commonly known as Vitamin C). None of his ideas concerning the medical usefulness of large doses of vitamins have gained much acceptance in the mainstream scientific community.<ref name="Horgan" /><ref name="Offit">{{Cite magazine |last=Offit |first=Paul |author-link=Paul Offit |date=July 19, 2013 |title=The Vitamin Myth: Why We Think We Need Supplements |url=https://www.theatlantic.com/health/archive/2013/07/the-vitamin-myth-why-we-think-we-need-supplements/277947/ |magazine=[[The Atlantic]] |language=en |issn=2151-9463 |oclc=936540106 |access-date=July 19, 2013 |url-access=subscription}}</ref> He was married to the American human rights activist [[Ava Helen Pauling]].
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