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Monellin
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{{short description|Protein}} {{infobox nonhuman protein | Name = '''Monellin Chain B''' | caption = X-ray crystal structure of an engineered single-chain monellin protein.<ref name="pmid17329805">{{PDB|2O9U}}; {{cite journal |vauthors=Hobbs JR, Munger SD, Conn GL | title = Monellin (MNEI) at 1.15 A resolution | journal = Acta Crystallographica Section F | volume = 63 | issue = Pt 3 | pages = 162β7 |date=March 2007 | pmid = 17329805 | pmc = 2330190 | doi = 10.1107/S1744309107005271 }}</ref> | image = hmonellin.png | Symbol = MonB | AltSymbols = | RefSeq = | UniProt = P02882 | PDB = 2O9U | PDB_supplemental = | Organism=Dioscoreophyllum cumminsii }} {{infobox nonhuman protein | Name = '''Monellin Chain A''' | Symbol = MonA | AltSymbols = | RefSeq = | UniProt = P02881 | PDB = 1IV7 | PDB_supplemental = | Organism=Dioscoreophyllum cumminsii }} {{Infobox protein family |Symbol=Monellin |InterPro=IPR015283 |Pfam=PF09200 }} '''Monellin''', a sweet [[protein]], was discovered in 1969 in the fruit of the West African shrub known as [[serendipity berry]] (''[[Dioscoreophyllum cumminsii]]''); it was first reported as a [[carbohydrate]].<ref name="jfs-34-408">GE Inglett, JF May. Serendipity berries - Source of a new intense sweetener. J Food Sci 1969, 34:408-411.</ref> The protein was named in 1972 after the [[Monell Chemical Senses Center]] in [[Philadelphia]], U.S.A., where it was isolated and characterized.<ref name="jbc-248-534">{{cite journal |vauthors=Morris JA, Martenson R, Deibler G, Cagan RH | title = Characterization of monellin, a protein that tastes sweet | journal = J. Biol. Chem. | volume = 248 | issue = 2 | pages = 534β9 |date=January 1973 | doi = 10.1016/S0021-9258(19)44407-4 | pmid = 4684691 | doi-access = free }}</ref>
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