Editing Nephrotoxicity (section)

{{Short description|Toxicity in the kidneys}}
'''Nephrotoxicity''' is [[toxicity]] in the [[kidney]]s. It is a [[poison]]ous effect of some [[chemical substance|substances]], both toxic chemicals and [[pharmaceutical drug|medications]], on [[kidney function]].<ref name=":0">{{Cite journal|last1=Abyar|first1=Selda|last2=Khandar|first2=Ali Akbar|last3=Salehi|first3=Roya|last4=Abolfazl Hosseini-Yazdi|first4=Seyed|last5=Alizadeh|first5=Effat|last6=Mahkam|first6=Mehrdad|last7=Jamalpoor|first7=Amer|last8=White|first8=Jonathan M.|last9=Shojaei|first9=Motahhareh|last10=Aizpurua-Olaizola|first10=O.|last11=Masereeuw|first11=Rosalinde|date=December 2019|title=In vitro nephrotoxicity and anticancer potency of newly synthesized cadmium complexes|journal=Scientific Reports|language=en|volume=9|issue=1|pages=14686|doi=10.1038/s41598-019-51109-9|issn=2045-2322|pmc=6789105|pmid=31604983|bibcode=2019NatSR...914686A }}</ref> There are various forms,<ref name="pmid10815380 ">{{cite journal |author=Galley HF |title=Can acute renal failure be prevented |journal=J R Coll Surg Edinb |volume=45 |issue=1 |pages=44–50 |year=2000 |pmid=10815380 |url=http://www.rcsed.ac.uk/journal/vol45_1/4510008.htm |url-status=dead |archive-url=https://web.archive.org/web/20051018104433/http://www.rcsed.ac.uk/journal/vol45_1/4510008.htm |archive-date=2005-10-18 }}</ref> and some drugs may affect kidney function in more than one way. '''Nephrotoxins''' are substances displaying nephrotoxicity.

Nephrotoxicity should not be confused with some medications predominantly excreted by the kidneys needing their dose adjusted for the decreased kidney function (e.g., [[heparin]], lithium).