Open main menu
Home
Random
Recent changes
Special pages
Community portal
Preferences
About Wikipedia
Disclaimers
Incubator escapee wiki
Search
User menu
Talk
Dark mode
Contributions
Create account
Log in
Editing
Nirenberg and Leder experiment
(section)
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
[[File:Marshall Nirenberg performing experiment.jpg|thumb|250px|Marshall Nirenberg]]The '''Nirenberg and Leder experiment''' was a scientific experiment performed in 1964 by [[Marshall W. Nirenberg]] and [[Philip Leder]]. The experiment elucidated the triplet nature of the [[genetic code]] and allowed the remaining ambiguous codons in the [[genetic code]] to be deciphered. In this experiment, using a [[ribosome]] binding [[assay]] called the [[#Experimental work|triplet binding assay]], various combinations of [[mRNA]] were passed through a filter which contained ribosomes. Unique triplets promoted the binding of specific [[tRNA]]s to the ribosome. By associating the tRNA with its specific [[amino acid]], it was possible to determine the triplet mRNA sequence that coded for each amino acid.
Edit summary
(Briefly describe your changes)
By publishing changes, you agree to the
Terms of Use
, and you irrevocably agree to release your contribution under the
CC BY-SA 4.0 License
and the
GFDL
. You agree that a hyperlink or URL is sufficient attribution under the Creative Commons license.
Cancel
Editing help
(opens in new window)