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Nutrient sensing
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{{Use dmy dates|date=December 2023}} '''Nutrient sensing''' is a [[cell (biology)|cell]]'s ability to recognize and respond to fuel substrates such as [[glucose]]. Each type of fuel used by the cell requires an alternate pathway of utilization and [[accessory molecule]]s such as [[enzyme]]s and [[Cofactor (biochemistry)|cofactor]]s. In order to conserve resources a cell will only produce molecules that it needs at the time. The level and type of fuel that is available to a cell will determine the type of [[enzymes]] it needs to express from its [[genome]] for utilization. [[Receptor (biochemistry)|Receptors]] on the [[cell membrane|cell membrane's]] surface designed to be activated in the presence of specific fuel molecules communicate to the [[cell nucleus]] via a means of [[cascading interactions]]. [[Nutrient receptor]]s are receptors that are primarily designed to perform the function of nutrient sensing, whereas other receptors (e.g. [[insulin receptor]]s, [[leptin receptor]]s) are extensively multifunctional and perform many functions besides nutrient sensing.<ref>{{Cite journal |last=A. Nguyen |first=C. |last2=Akiba |first2=Y. |last3=D. Kaunitz |first3=J. |date=2012-01-01 |title=Recent Advances in Gut Nutrient Chemosensing |url=https://www.ingentaconnect.com/content/ben/cmc/2012/00000019/00000001/art00005 |journal=Current Medicinal Chemistry |volume=19 |issue=1 |pages=28β34 |doi=10.2174/092986712803414033|pmc=4845632 }}</ref> In this way the cell is aware of the available nutrients and is able to produce only the molecules specific to that nutrient type.
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