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Stephen Altschul
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{{short description|American mathematician|bot=PearBOT 5}} {{Infobox scientist |birth_name = Stephen Frank Altschul |image = |birth_date = {{Birth date and age|1957|02|28}} |birth_place = |death_date = |death_place = |residence = |citizenship = [[United States]] |nationality = |ethnicity = |field = [[Bioinformatics]] |work_institutions = [[National Center for Biotechnology Information|NCBI]] |alma_mater = [[Harvard University]] (A.B., Mathematics)<br>[[Massachusetts Institute of Technology]] (Ph.D., Mathematics) |doctoral_advisor = [[Daniel Kleitman]]<ref name="mathgene">{{MathGenealogy|id=64861}}</ref> | thesis_title = Aspects of Biological Sequence Comparison | thesis_url = https://www.proquest.com/docview/303525377/ | thesis_year = 1987 |doctoral_students = |known_for = [[BLAST (biotechnology)|BLAST]] |influences = |influenced = |prizes = | website = {{URL|https://www.ncbi.nlm.nih.gov/research/staff/altschul}} |spouse=Caroline Kershaw James (m. 1994) }} '''Stephen Frank Altschul''' (born February 28, 1957) is an American [[mathematician]] who has designed [[algorithm]]s that are used in the field of [[bioinformatics]] (the Karlin–Altschul algorithm<ref>{{Cite journal | last1 = Altschul | first1 = S. | authorlink1 = Stephen Altschul | last2 = Gish | first2 = W. | authorlink2 = Warren Gish | last3 = Miller | first3 = W. | authorlink3 = Webb Miller | last4 = Myers | first4 = E. | authorlink4 = Eugene Myers | last5 = Lipman | first5 = D. | authorlink5 = David J. Lipman | title = Basic Local Alignment Search Tool | doi = 10.1016/S0022-2836(05)80360-2 | journal = Journal of Molecular Biology | volume = 215 | issue = 3 | pages = 403–410 | year = 1990 | pmid = 2231712 | pmc = | s2cid = 14441902 }}</ref> and its successors<ref>{{Cite journal | last1 = Altschul | first1 = S. | authorlink1 = Stephen Altschul| last2 = Madden | first2 = T. L. | last3 = Schäffer | first3 = A. A. | last4 = Zhang | first4 = J. | last5 = Zhang | first5 = Z. | last6 = Miller | first6 = W. | authorlink6 = Webb Miller| last7 = Lipman | first7 = D. J. | authorlink7 = David J. Lipman| title = Gapped BLAST and PSI-BLAST: A new generation of protein database search programs | doi = 10.1093/nar/25.17.3389 | journal = Nucleic Acids Research | volume = 25 | issue = 17 | pages = 3389–3402 | year = 1997 | pmid = 9254694| pmc =146917 }}</ref>). Altschul is the co-author of the [[BLAST (biotechnology)|BLAST]] algorithm used for [[sequence analysis]] of [[protein]]s and [[nucleotide]]s.<ref name="microsoft">{{AcademicSearch|2212030}}</ref><ref name="dblp">{{DBLP|name=Stephen F. Altschul}}</ref>
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