Editing Structural bioinformatics (section)

{{Short description|Bioinformatics subfield}}
[[File:1kqf opm.png|thumb|220px|Three-dimensional structure of a protein]]

'''Structural bioinformatics''' is the branch of [[bioinformatics]] that is related to the analysis and prediction of the three-dimensional structure of biological [[macromolecules]] such as [[proteins]], [[RNA]], and [[DNA]]. It deals with generalizations about macromolecular 3D structures such as comparisons of overall folds and local motifs, principles of molecular folding, evolution, binding interactions, and structure/function relationships, working both from experimentally solved structures and from computational models. The term ''structural'' has the same meaning as in [[structural biology]], and structural bioinformatics can be seen as a part of computational structural biology. The main objective of structural bioinformatics is the creation of new methods of analysing and manipulating biological macromolecular data in order to solve problems in biology and generate new knowledge.<ref>{{Cite book|last1=Gu | first1 = Jenny | last2 = Bourne | first2 = Philip E.| name-list-style = vanc |title=Structural Bioinformatics |date=2011|publisher=John Wiley & Sons|isbn=978-1-118-21056-7|edition= 2nd|location=Hoboken|oclc=778339075}}</ref>