Editing Terminator (genetics) (section)

{{short description|Section of genetic sequence that marks the end of gene or operon on genomic DNA for transcription}}

In [[genetics]], a '''transcription terminator''' is a section of [[nucleic acid]] sequence that marks the end of a [[gene]] or [[operon]] in genomic [[DNA]] during [[Transcription (genetics)|transcription]]. This sequence mediates transcriptional termination by providing signals in the newly synthesized transcript RNA that trigger processes which release the  transcript RNA from the [[RNA polymerase|transcriptional complex]]. These processes include the direct interaction of the [[Nucleic acid secondary structure|mRNA secondary structure]] with the complex and/or the indirect activities of recruited [[termination factor]]s. Release of the transcriptional complex frees [[RNA polymerase]] and related transcriptional machinery to begin transcription of new mRNAs.