Editing Thioester (section)

{{short description|1=Organosulfur compounds of the form R–SC(=O)–R’}}

{{Redirect|Thioate|the ion class|thiocarboxylic acid}}
[[Image:Thioester-2D-A.svg|thumb|class=skin-invert-image|right|150px|General structure of a thioester, where R and R' are [[organyl]] groups, or [[Hydrogen|H]] in the case of R.]]
In [[organic chemistry]],  '''thioesters''' are [[organosulfur compounds]] with the molecular structure {{chem2|R\sC(\dO)\sS\sR’}}. They are analogous to [[carboxylate ester]]s ({{chem2|R\sC(\dO)\sO\sR’}}) with the sulfur in the thioester replacing oxygen in the carboxylate ester, as implied by the [[thio-]] prefix. They are the product of [[esterification]] of a [[carboxylic acid]] ({{chem2|R\sC(\dO)\sO\sH}}) with a [[thiol]] ({{chem2|R'\sS\sH}}). In [[biochemistry]], the best-known thioesters are derivatives of [[coenzyme A]], e.g., [[acetyl-CoA]].<ref name=PATAI>Matthys J. Janssen "Carboxylic Acids and Esters" in PATAI's Chemistry of Functional Groups: Carboxylic Acids and Esters, Saul Patai, Ed. John Wiley, 1969, New York: pp. 705–764.  {{doi|10.1002/9780470771099.ch15}}</ref> The R and R' represent [[organyl]] groups, or [[Hydrogen|H]] in the case of R.