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Tropical sprue
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{{Other uses|Sprue (disambiguation){{!}}Sprue}} {{Infobox medical condition (new) | name = Tropical sprue | image = | caption = | | pronounce = | field = | synonyms = Postinfectious tropical malabsorption<ref name="Wanke2015" /> | symptoms = Diarrhoea, abdominal pain, weight loss | complications = Malabsorption, anaemia | onset = | duration = | types = | causes = | risks = | diagnosis = Intestinal histology | differential = Coeliac disease, environmental enteropathy | prevention = | treatment = Antibiotics, folate replacement | medication = | prognosis = | frequency = | deaths = }} '''Tropical sprue''' is a [[malabsorption]] disease commonly found in tropical regions, marked with abnormal flattening of the [[Intestinal villus|villi]] and [[inflammation]] of the lining of the [[small intestine]].<ref name="Wanke2015">{{cite book| author=Wanke, Christine A. | chapter=Tropical Sprue: enteropathy |title=Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases|editor1=Bennett, John E.|editor2=Dolin, Raphael|editor3=Blaser, Martin J.| edition=8| date=2015| pages=1297β1301 | doi=10.1016/B978-1-4557-4801-3.00104-1 | pmc=7151975|chapter-url=https://books.google.com/books?id=73pYBAAAQBAJ&pg=PA1298}}</ref><ref name="pmid17148698">{{cite journal |vauthors=Ramakrishna BS, Venkataraman S, Mukhopadhya A |title=Tropical malabsorption |journal=Postgrad Med J |volume=82 |issue=974 |pages=779β87 |year=2006 |pmid=17148698 |pmc=2653921 |doi=10.1136/pgmj.2006.048579 }}</ref> It differs significantly from [[coeliac sprue]]. It appears to be a more severe form of [[environmental enteropathy]].<ref name="pmid22633998">{{cite journal |vauthors=Korpe PS, Petri WA |title=Environmental enteropathy: critical implications of a poorly understood condition |journal=Trends Mol Med |volume=18 |issue=6 |pages=328β36 |year=2012 |pmid=22633998 |pmc=3372657 |doi=10.1016/j.molmed.2012.04.007 }}</ref><ref name="pmid24781741">{{cite journal |vauthors=Ghoshal UC, Srivastava D, Verma A, Ghoshal U |title=Tropical sprue in 2014: the new face of an old disease |journal=Curr Gastroenterol Rep |volume=16 |issue=6 |pages=391 |year=2014 |pmid=24781741 |doi=10.1007/s11894-014-0391-3 |pmc=7088824 }}</ref>
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