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World Community Grid
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{{Short description|BOINC based volunteer computing project to aid scientific research}} {{Infobox distributed computing project | logo = Worldcommunitygrid.png | logo_size = 250px | developer = {{Unbulleted list | [[United Devices]] | [[IBM]] | [[Krembil Research Institute]]}} | released = {{start date |2004|11|16}}<ref name="WCG introduced">{{cite press release |url=http://www-03.ibm.com/industries/healthcare/us/detail/news/Y344005K66783Y35.html |title=IBM Introduces 'World Community Grid' |publisher=[[IBM]] |date=16 November 2004 |access-date=11 February 2009 |archive-date=5 September 2022 |archive-url=https://web.archive.org/web/20220905052727/https://www.ibm.com/industries/healthcare |url-status=dead }}</ref> | latest release version = 7.16.19 | status = Active | operating system = {{nobr|β’ [[Microsoft Windows]] }}<br/>{{nobr|β’ [[Linux]]}}<br/>{{nobr|β’ [[macOS]]}}<br/>{{nobr|β’ [[Android (operating system)|Android]]}}<br/>{{nobr|β’ [[Raspberry Pi OS]]}} | platform = [[BOINC]] | genre = [[Volunteer computing]] | performance = 402 [[FLOPS|TFLOPS]]<ref name=STATS>{{Cite web | url=https://www.boincstats.com/stats/15/project/detail/ | title=BOINCStats | access-date=2023-06-19 | archive-date=2023-04-05 | archive-url=https://web.archive.org/web/20230405231644/https://www.boincstats.com/stats/15/project/detail | url-status=live }}</ref> | active users = 23,248{{r|STATS}} | total users = 79,354{{r|STATS}} | active hosts = 57,672{{r|STATS}} | total hosts = 5,517,865{{r|STATS}} | website = {{url|1=https://www.worldcommunitygrid.org/}} or try {{url|2=https://www.cs.toronto.edu/~juris/jlab/wcg.html}} | motto = "Let your computer daydream science" | type = [[Volunteer computing]] project |screenshot=Pandemics.gif|screenshot_size=250px}} '''World Community Grid''' ('''WCG''') is an effort to create the world's largest [[volunteer computing]] platform to perform scientific research that benefits humanity.<ref name="About Us">{{cite web |url=http://www.worldcommunitygrid.org/about_us/viewAboutUs.do |title=About Us |publisher=World Community Grid |access-date=28 July 2007 |archive-date=19 April 2022 |archive-url=https://web.archive.org/web/20220419195719/https://www.worldcommunitygrid.org/about_us/viewAboutUs.do |url-status=live }}</ref> Launched on November 16, 2004, with proprietary [[Grid MP]] client from [[United Devices]] and adding support for [[BOINC|Berkeley Open Infrastructure for Network Computing (BOINC)]] in 2005, World Community Grid eventually discontinued the Grid MP client and consolidated on the BOINC platform in 2008.<ref name="bbover3">{{cite web |author=bbover3 |date=2007-08-17 |title=BOINC Migration Announcement |url=http://www.worldcommunitygrid.org/forums/wcg/viewthread?thread=15715 |access-date=2007-08-17 |publisher=World Community Grid |archive-date=2018-11-03 |archive-url=https://web.archive.org/web/20181103032930/https://www.worldcommunitygrid.org/forums/wcg/viewthread?thread=15715 |url-status=live }}</ref> In September 2021, it was announced that IBM transferred ownership to the [[Krembil Research Institute]] of [[University Health Network]] in [[Toronto]], [[Ontario]].<ref name=":1">{{Cite web|title=World Community Grid finds a new home at Krembil Research Institute|url=https://www.worldcommunitygrid.org/about_us/viewNewsArticle.do?articleId=732|access-date=2021-09-13|website=www.worldcommunitygrid.org |archive-url=https://web.archive.org/web/20210913180104/https://www.worldcommunitygrid.org/about_us/viewNewsArticle.do?articleId=732 |archive-date=2021-09-13 |url-status=live}}</ref> World Community Grid uses unused processing power of consumer devices (PCs, Laptops, Android Smartphones, etc.) to analyse data created by the research groups that participate in the grid. WCG projects have analysed data related to the [[human genome]], the [[human microbiome]], [[HIV]], [[dengue]], [[muscular dystrophy]], [[cancer]], [[influenza]], [[Ebola]], [[Zika virus]], [[virtual screening]], [[rice|rice crop yields]], [[green energy|clean energy]], [[water purification]] and [[Coronavirus disease 2019|COVID-19]], among other research areas.<ref name="ibm.org">{{Cite web|url=https://www.ibm.org/OpenPandemics|title=We want to stop pandemics in their tracks.|date=2020-04-01|website=IBM.org|access-date=2020-04-03|archive-date=2020-04-08|archive-url=https://web.archive.org/web/20200408055441/https://www.ibm.org/OpenPandemics|url-status=live}}</ref> There are currently five active projects and 26 completed projects.<ref>{{Cite web|title=Research Overview|url=https://www.worldcommunitygrid.org/research/viewAllProjects.do|access-date=2021-04-17|website=www.worldcommunitygrid.org|archive-date=2022-04-18|archive-url=https://web.archive.org/web/20220418074921/https://www.worldcommunitygrid.org/research/viewAllProjects.do|url-status=live}}</ref> Several of these projects have published peer-reviewed papers based on the analysis of the data generated by WCG. These include an OpenZika project paper on the discovery of a compound (FAM 3) that inhibits the NS3 [[Helicase]] protein of the Zika virus, thus reducing viral replication by up to 86%;<ref>{{cite journal | vauthors = Silva S, Shimizu JF, Oliveira DM, Assis LR, Bittar C, Mottin M, Sousa BK, Mesquita NC, Regasini LO, Rahal P, Oliva G, Perryman AL, Ekins S, Andrade CH, Goulart LR, Sabino-Silva R, Merits A, Harris M, Jardim AC | display-authors = 6 | title = A diarylamine derived from anthranilic acid inhibits ZIKV replication | journal = Scientific Reports | volume = 9 | issue = 1 | pages = 17703 | date = November 2019 | pmid = 31776405 | pmc = 6881388 | doi = 10.1038/s41598-019-54169-z | bibcode = 2019NatSR...917703S }}</ref><ref>{{Cite web|url=https://www.worldcommunitygrid.org/about_us/displayNews.do|title=World Community Grid - News|access-date=2020-03-17|archive-date=2020-03-23|archive-url=https://web.archive.org/web/20200323051304/https://www.worldcommunitygrid.org/about_us/displayNews.do|url-status=live}}</ref> a FightAIDS@home paper on the discovery of new vulnerabilities on the HIV-1 [[Capsid|Capsid protein]] which may allow for a new drug target;<ref>{{cite journal | vauthors = Craveur P, Gres AT, Kirby KA, Liu D, Hammond JA, Deng Y, Forli S, Goodsell DS, Williamson JR, Sarafianos SG, Olson AJ | display-authors = 6 | title = Novel Intersubunit Interaction Critical for HIV-1 Core Assembly Defines a Potentially Targetable Inhibitor Binding Pocket | journal = mBio | volume = 10 | issue = 2 | date = March 2019 | pmid = 30862755 | doi = 10.1128/mBio.02858-18 |pmc=6414707 | doi-access = free }}</ref><ref>{{Cite web|title=FightAIDS@Home β Phase 1 researchers identified new potential targets for antivirals|url=https://www.worldcommunitygrid.org/about_us/viewNewsArticle.do?articleId=629|access-date=2021-04-17|website=www.worldcommunitygrid.org}}</ref> and a FightAIDS@home paper on new computational drug discovery techniques for more refined and accurate results.<ref>{{cite journal | vauthors = Xia J, Flynn W, Gallicchio E, Uplinger K, Armstrong JD, Forli S, Olson AJ, Levy RM | display-authors = 6 | title = Massive-Scale Binding Free Energy Simulations of HIV Integrase Complexes Using Asynchronous Replica Exchange Framework Implemented on the IBM WCG Distributed Network | journal = Journal of Chemical Information and Modeling | volume = 59 | issue = 4 | pages = 1382β1397 | date = April 2019 | pmid = 30758197 | pmc = 6496938 | doi = 10.1021/acs.jcim.8b00817 }}</ref><ref>{{Cite web|title=FightAIDS@Home Team's New Simulation Technique Published in Industry Journal|url=https://www.worldcommunitygrid.org/about_us/viewNewsArticle.do?articleId=593|access-date=2021-04-17|website=www.worldcommunitygrid.org|archive-date=2021-04-17|archive-url=https://web.archive.org/web/20210417212628/https://www.worldcommunitygrid.org/about_us/viewNewsArticle.do?articleId=593|url-status=live}}</ref>
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