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==Mathematics== * [[René Descartes]] promotes intellectual rigour in ''[[Discourse on the Method|Discours de la méthode pour bien conduire sa raison, et chercher la vérité dans les sciences]]'' and introduces the [[Cartesian coordinate system]] in its appendix ''[[La Géométrie]]'' (published in [[Leiden]]).<ref>{{cite book|first=Tony|last=Crilly|title=50 Mathematical Ideas you really need to know|location=London|publisher=Quercus|year=2007|isbn=978-1-84724-008-8|page=68}}</ref> * [[Pierre de Fermat]] conjectures [[Fermat's Last Theorem]].
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