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Adderall
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==Uses== {{multiple image <!-- Essential parameters --> | align = right | direction = vertical | width = 300 <!-- Extra parameters --> | image1=30xAdderall10mg.jpg | caption1=30 capsules of 10 mg Adderall XR | alt1=30 Adderall XR 10 mg capsules | image2=Amph salts.jpg | caption2=A group of 20 mg Adderall tablets, some broken in half, with a lengthwise-folded US dollar bill along the bottom (3.07 inches; 7.8 cm) for size comparison | alt2=Adderall 20 mg tablets }} ===Medical=== Adderall is commonly used to treat [[attention deficit hyperactivity disorder]] (ADHD) and [[narcolepsy]].<ref name="Amphetamine Formulations Review" /><ref>{{Cite web |title=Adderall and Prescription Amphetamines |url=https://redemptionrecoverygroup.com/addiction-recovery-resources/adderall-and-prescription-amphetamines/ |access-date=2025-03-21 |website=Redemption Recovery |language=en-US}}</ref><ref name="Adderall IR">{{cite web |date=November 8, 2019 |title=Adderall- dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablet |url=https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f22635fe-821d-4cde-aa12-419f8b53db81 |url-status=live |archive-url=https://web.archive.org/web/20191002150413/https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f22635fe-821d-4cde-aa12-419f8b53db81 |archive-date=October 2, 2019 |access-date=December 22, 2019 |website=DailyMed |publisher=Teva Pharmaceuticals USA, Inc.}}</ref> ====ADHD==== <!-- PLEASE NOTE: the following content is transcluded from its parent article [[amphetamine]]. If you wish to alter content on ADHD, then go to [[amphetamine#ADHD]] and edit the source code there. After you finalise your edit, it will render here accordingly --> {{#lsth:Amphetamine|ADHD}} ====Narcolepsy==== <!-- PLEASE NOTE: the following content is transcluded from its parent article [[amphetamine]]. If you wish to alter content on narcolepsy, then go to [[amphetamine#Narcolepsy]] and edit the source code there. After you finalise your edit, it will render here accordingly --> {{#lsth:Amphetamine|Narcolepsy}} ====Available forms==== Adderall is available as [[immediate-release]] (IR) tablets and [[extended-release]] (XR) capsules.<ref name="Adderall IR" /><ref name="Adderall XR all pages">{{cite web | title = Adderall XR Prescribing Information | url = https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/021303s026lbl.pdf | publisher = Shire US Inc | website = United States Food and Drug Administration | date = December 2013 | access-date = 30 December 2013 | archive-date = 30 December 2013 | archive-url = https://web.archive.org/web/20131230233702/http://www.accessdata.fda.gov/drugsatfda_docs/label/2013/021303s026lbl.pdf | url-status = live}}</ref> Mydayis is only available as an extended-release formulation.<ref name="Mydayis medication">{{Cite web|url=http://pi.shirecontent.com/PI/PDFs/Mydayis_USA_ENG.pdf|title=Mydayis medication guide|website=Mydayis.com|language=en|access-date=6 February 2024|date=October 2023}}</ref> Adderall XR is approved to treat ADHD for up to 12 hours in individuals 6 years and older and uses a [[Modified-release dosage|double-bead formulation]]. The capsule can be swallowed like a tablet, or it can be opened and the beads sprinkled over applesauce for comparable absorption.<ref name="Adderall XR all pages" /> Upon ingestion, half of the beads provide immediate administration of medication, while the other half are enveloped in a coating that must dissolve, delaying absorption of its contents. It is designed to provide a therapeutic effect and plasma concentrations identical to taking two doses of Adderall IR four hours apart.<ref name="Adderall XR all pages" /> Mydayis uses a longer-lasting triple-bead formulation and is approved to treat ADHD for up to 16 hours in individuals 13 years and older.<ref name="Mydayis medication" /> In the [[United States]], the immediate and extended-release formulations of Adderall are both available as [[generic drug]]s.<ref>{{Cite web|url=https://www.drugs.com/availability/generic-adderall.html|title=Generic Adderall Availability|website=Drugs.com|language=en|access-date=6 February 2020|archive-date=28 May 2020|archive-url=https://web.archive.org/web/20200528223452/https://www.drugs.com/availability/generic-adderall.html|url-status=live}}</ref><ref>{{Cite web|url=https://www.drugs.com/availability/generic-adderall-xr.html|title=Generic Adderall XR Availability|website=Drugs.com|language=en|access-date=6 February 2020|archive-date=6 February 2020|archive-url=https://web.archive.org/web/20200206144135/https://www.drugs.com/availability/generic-adderall-xr.html|url-status=live}}</ref> Generic formulations of Mydayis became available in the US in October 2023.<ref>{{Cite web|url=https://professionals.optumrx.com/content/dam/optum3/professional-optumrx/news/rxnews/new-generics/newgenerics_mydayis_2023-1012.pdf|title=Mydayis® (mixed-salts of a single-entity amphetamine product) – First-time generic|website=OptumRx|language=en|access-date=6 February 2023}}</ref> ===Enhancing performance=== {{transcluded section|source=Amphetamine|part=yes}} {{trim|{{#section-h:Amphetamine|Enhancing performance}}}} Adderall has been banned in the [[National Football League]] (NFL), [[Major League Baseball]] (MLB), [[National Basketball Association]] (NBA), and the [[National Collegiate Athletic Association|National Collegiate Athletics Association]] (NCAA).<ref name="Leon">{{cite web| vauthors = Moore DL |title=Do pro sports leagues have an Adderall problem?|publisher=USA TODAY|access-date=4 May 2014|url= https://www.usatoday.com/story/sports/nfl/2012/11/27/adderall-in-pro-sports/1730431/ |archive-date=23 November 2014|archive-url= https://web.archive.org/web/20141123131934/http://www.usatoday.com/story/sports/nfl/2012/11/27/adderall-in-pro-sports/1730431/ |url-status=live}}</ref> In leagues such as the [[National Football League|NFL]], there is a very rigorous process required to obtain an exemption to this rule even when the athlete has been medically prescribed the drug by their physician.<ref name="Leon" /> ===Recreational=== {{See also|History and culture of substituted amphetamines}} Adderall has a high potential for misuse as a [[recreational drug use|recreational drug]].<ref>{{cite web |url=http://www.drugabuse.gov/drugs-abuse/commonly-abused-drugs/commonly-abused-prescription-drugs-chart |title=Commonly Abused Prescription Drugs Chart |publisher=National Institute on Drug Abuse |access-date=7 May 2012 |archive-url=https://web.archive.org/web/20120501092302/http://www.drugabuse.gov/drugs-abuse/commonly-abused-drugs/commonly-abused-prescription-drugs-chart |archive-date=1 May 2012 |url-status=dead}}</ref><ref>{{cite web |url=http://www.drugabuse.gov/publications/infofacts/stimulant-adhd-medications-methylphenidate-amphetamines |title=Stimulant ADHD Medications – Methylphenidate and Amphetamines |publisher=National Institute on Drug Abuse |access-date=7 May 2012 |archive-date=2 May 2012 |archive-url=https://web.archive.org/web/20120502072325/http://www.drugabuse.gov/publications/infofacts/stimulant-adhd-medications-methylphenidate-amphetamines |url-status=dead}}</ref><ref name="Abelman 68">{{Cite journal| vauthors = Abelman DD |date=6 October 2017|title=Mitigating risks of students use of study drugs through understanding motivations for use and applying harm reduction theory: a literature review|journal=Harm Reduction Journal|volume=14|issue=1|pages=68|doi=10.1186/s12954-017-0194-6|pmid=28985738|pmc=5639593|issn=1477-7517 |doi-access=free}}</ref> Adderall tablets can either be swallowed, crushed and snorted, or dissolved in water and injected.<ref name="NIDA">{{cite web|title=National Institute on Drug Abuse. 2009. Stimulant ADHD Medications – Methylphenidate and Amphetamines|url=https://nida.nih.gov/publications/research-reports/misuse-prescription-drugs/overview|publisher=National Institute on Drug Abuse|access-date=27 February 2013|archive-url=https://web.archive.org/web/20130312110514/http://www.drugabuse.gov/publications/drugfacts/stimulant-adhd-medications-methylphenidate-amphetamines|archive-date=12 March 2013|url-status=dead}}</ref> Injection into the bloodstream can be dangerous because [[Excipient|insoluble fillers within the tablets]] can block small blood vessels.<ref name="NIDA" /> Many postsecondary students have reported using Adderall for study purposes in different parts of the developed world.<ref name="Abelman 68" /> Among these students, some of the [[risk factor]]s for misusing ADHD stimulants recreationally include: possessing [[deviance (sociology)|deviant personality]] characteristics (i.e., exhibiting delinquent or deviant behavior), inadequate accommodation of disability, basing one's [[self-worth]] on external validation, low [[self-efficacy]], earning poor grades, and having an untreated [[mental health disorder]].<ref name="Abelman 68" />
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