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==History== The brand first entered the American market in 1984 through [[Whitehall-Robins|Whitehall]]<ref name=cases>{{cite book | title=Pharmaceutical Marketing: Strategy and Cases | publisher=CRC Press | author=Smith, Mickey C. | year=1991 | pages=319 | isbn=9781439810910}}</ref> (itself a division of [[Wyeth]], which was purchased by [[Pfizer]] in 2009),<ref name="nature">Sheridan, C. "Pfizer swallows Wyeth, validates niche buster." ''Nat Biotechnol'' '''27''', 218β219 (2009). https://doi.org/10.1038/nbt0309-218.</ref> the same year ibuprofen gained [[Food and Drug Administration]] (FDA) approval for [[over-the-counter]] (OTC) sales in the United States (being available via prescription since 1974).<ref name="nineteen Eighty-Four">{{cite news | url=https://nyti.ms/4d9wgcC | title=Scramble Over Pain Relievers | work=The New York Times | date=June 4, 1984 | author=Hollie, Pamela G. | page=D1}}</ref><ref>[https://www.newspapers.com/article/the-columbus-ledger/172056852/ Full-page advertisement], ''[[Columbus Leader]]'', November 25, 1984, page 195.</ref> Advil and a competing OTC ibuprofen brand, Nuprin, were first announced to the public on May 18, 1984, the same day that the FDA approved OTC sales of ibuprofen. Within a week of the announcement, Advil was available for purchase at some stores.<ref>[https://www.newspapers.com/article/the-kalamazoo-gazette/172056945/ "Upjohn drug gets FDA OK"], ''[[Kalamazoo Gazette]]'', May 19, 1984, front page.</ref><ref>[https://www.newspapers.com/article/the-courier-news/172057308/ Advertisement], ''[[Courier News]]'', May 26, 1984, page 4.</ref> Within ten years of having a market presence, it outsold [[Bayer Aspirin]] and was a fierce competitor to [[Tylenol (brand)|Tylenol]] (primarily a brand of [[acetaminophen]]).<ref name="excellence">{{cite book | title=Icons of the American Marketplace: Consumer Brand Excellence | publisher=American Benchmark Press | year=2007 | pages=8 | isbn=9780307383457}}</ref> In the mid-1990s, for example, it held 13% of the multibillion-dollar over-the-counter American market for [[analgesics]].<ref name="ibuprofen">{{cite book | title=Ibuprofen: A Critical Bibliographic Review | publisher=CRC Press | author=Rainsford, Kim D. | year=2003 | pages=424 | isbn=9780203362587}}</ref>
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