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Alcohol intoxication
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==Symptoms== {{See also|Short-term effects of alcohol consumption}} * [[Vomiting]]<ref name=":0" /> * [[Bradypnea|Slow breathing]] (fewer than eight breaths per minute)<ref name=":1" /> * [[Seizure|Seizures]]<ref name=":2" /> * [[pallor|Blue, grey or pale skin]]<ref name=":3" /> * [[Hypothermia]] (Low body temperature)<ref name=":4" /> * [[Lethargy]] (Trouble staying conscious)<ref name=":5" /> [[File:The wine is a mocker 1663-1664 Jan Steen.jpg|thumb|upright=1.4|''Wine is a Mocker'' by [[Jan Steen]] {{circa}} 1663]] Alcohol intoxication leads to negative health effects due to the recent drinking of large amount of [[ethanol]] (alcohol).<ref name=Jun2014/><ref>{{cite web |last=Latham |first=Katherine |date=2022-12-11 |title='Alcohol affects every organ': hangovers and how to survive them |url=https://www.theguardian.com/society/2022/dec/11/alcohol-affects-every-organ-hangovers-and-how-to-survive-them |access-date=2023-01-05 |website=The Guardian}}</ref> When severe it may become a [[medical emergency]]. Some effects of alcohol intoxication, such as euphoria and lowered [[social inhibition]], are central to alcohol's desirability.<ref>{{cite book |last=Dudley |first=Robert |title=The drunken monkey: why we drink and abuse alcohol |date=May 2014 |isbn=978-0-520-95817-3 |location=Berkeley |oclc=869457130}}</ref> As drinking increases, people become sleepy or fall into a [[stupor]]. At very high [[blood alcohol concentration]]s, for example above 0.3%, the respiratory system becomes depressed and the person may stop breathing.<ref>{{cite web |title=Students > Alcohol Effects |url=http://www.alcohol.vt.edu/Students/alcoholEffects/index.htm |website=Virginia Tech |date=5 May 2007|archive-url=https://web.archive.org/web/20070505032342/http://www.alcohol.vt.edu/Students/alcoholEffects/index.htm |archive-date=5 May 2007 }}</ref> Comatose patients may aspirate their vomit (resulting in vomitus in the lungs, which may cause "drowning" and later [[pneumonia]] if survived). CNS depression and impaired motor coordination along with poor judgment increase the likelihood of accidental injury occurring. It is estimated that about one-third of alcohol-related deaths are due to accidents and another 14% are from intentional injury.<ref>The World Health Organization (2007) Alcohol and Injury in Emergency Departments</ref> In addition to respiratory failure and accidents caused by its effects on the central nervous system, alcohol causes significant metabolic derangements. [[Hypoglycaemia]] occurs due to ethanol's inhibition of [[gluconeogenesis]], especially in children, and may cause [[lactic acidosis]], [[ketoacidosis]], and [[acute kidney injury]]. Metabolic acidosis is compounded by respiratory failure. Patients may also present with hypothermia.
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