Editing Anaphylaxis (section)

==Cause, mechanism, and diagnosis==
Common causes include allergies to [[insect bite]]s and stings, [[Food allergy|allergies to foods]]—including nuts, milk, fish, shellfish, eggs and some fresh fruits or dried fruits; allergies to sulfites—a class of food preservatives and a byproduct in some fermented foods like vinegar; allergies to medications – including some antibiotics and non-steroidal anti-inflammatory drugs (NSAIDs) like aspirin;<ref>{{Cite book |title=Oxford Handbook of Emergency Medicine |publisher=Oxford Medical Productions |edition=4th |page=42}}</ref> allergy to general anaesthetic (used to make people sleep during surgery); allergy to contrast agents – dyes used in some medical tests to help certain areas of the body show up better on scans; allergy to [[latex]] – a type of rubber found in some rubber gloves and condoms.<ref name="Overview - Anaphylaxis"/><ref name=NIH2015/> Other causes can include physical exercise, and cases may also occur in some people due to escalating reactions to simple throat irritation or may also occur without an obvious reason.<ref name="Overview - Anaphylaxis"/><ref name=NIH2015>{{cite web|title=Anaphylaxis|url=https://www.niaid.nih.gov/topics/anaphylaxis/Pages/default.aspx|publisher=National Institute of Allergy and Infectious Diseases|access-date=4 February 2016|date=April 23, 2015|archive-url=https://web.archive.org/web/20150504041904/http://www.niaid.nih.gov/topics/anaphylaxis/Pages/default.aspx|archive-date=4 May 2015}}</ref> The mechanism involves the release of inflammatory mediators in a rapidly escalating cascade from certain types of [[white blood cell]]s triggered by either [[Immune system|immunologic]] or non-immunologic mechanisms.<ref name=Khan11>{{cite journal|last=Khan|first=BQ|author2=Kemp, SF|title=Pathophysiology of anaphylaxis|journal=Current Opinion in Allergy and Clinical Immunology|date=August 2011|volume=11|issue=4|pages=319–25|pmid=21659865|doi=10.1097/ACI.0b013e3283481ab6|s2cid=6810542}}</ref> Diagnosis is based on the presenting symptoms and signs after exposure to a potential [[allergen]] or irritant and in some cases, reaction to physical exercise.<ref name="Overview - Anaphylaxis"/><ref name=NIH2015/>