Editing Bad trip (section)

== Signs and symptoms ==
{{See also|Psychosis|Substance-induced psychosis}}
With proper screening, preparation, and support in a regulated setting these are usually benign.<ref>{{cite journal |last1=Barrett |first1=FS |last2=Bradstreet |first2=MP |last3=Leoutsakos |first3=JS |last4=Johnson |first4=MW |last5=Griffiths |first5=RR |date=December 2016 |title=The Challenging Experience Questionnaire: Characterization of challenging experiences with psilocybin mushrooms. |journal=Journal of Psychopharmacology |volume=30 |issue=12 |pages=1279–1295 |doi=10.1177/0269881116678781 |pmc=5549781 |pmid=27856683}}</ref> A bad trip on [[psilocybin]], for instance, often features intense anxiety, confusion, agitation, and [[psychosis]].<ref name="van-amsterdam-et-al">{{Cite journal |last1=van Amsterdam |first1=Jan |last2=Opperhuizen |first2=Antoon |last3=van den Brink |first3=Wim |date=2011 |title=Harm potential of magic mushroom use: A review |journal=Regulatory Toxicology and Pharmacology |volume=59 |issue=3 |pages=423–429 |doi=10.1016/j.yrtph.2011.01.006 |pmid=21256914}}</ref> They manifest as a range of feelings, such as anxiety, paranoia, the unshakeable sense of one's inevitable and imminent personal demise or states of unrelieved terror that they believe will persist after the substance's [[Pharmacokinetics#LADME|effects]] have worn off. As of 2011, exact data on the frequency of bad trips are not available.<ref name="van-amsterdam-et-al" />