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Cecum
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==Structure== [[File:Diameters of the large intestine.svg|thumb|Inner diameters of different sections of the large intestine, with cecum (at bottom left) measuring on average 8.7 cm (range 8.0-10.5 cm).<ref name=Nguyen>{{cite journal |vauthors=Nguyen H, Loustaunau C, Facista A, Ramsey L, Hassounah N, Taylor H, Krouse R, Payne CM, Tsikitis VL, Goldschmid S, Banerjee B, Perini RF, Bernstein C |title=Deficient Pms2, ERCC1, Ku86, CcOI in field defects during progression to colon cancer |journal=J Vis Exp |issue=41 |year=2010 |pmid=20689513 |pmc=3149991 |doi=10.3791/1931 }}</ref>]] ===Development=== The cecum and appendix are derived from the bud of cecum that forms during week six in the midgut next to the apex of the umbilical herniation.<ref name="lie">{{cite journal |last1=Kostouros |first1=Antonios |last2=Koliarakis |first2=Ioannis |last3=Natsis |first3=Konstantinos |last4=Spandidos |first4=Demetrios |last5=Tsatsakis |first5=Aristidis |last6=Tsiaoussis |first6=John |title=Large intestine embryogenesis: Molecular pathways and related disorders (Review) |journal=International Journal of Molecular Medicine |date=21 April 2020 |volume=46 |issue=1 |pages=27β57 |doi=10.3892/ijmm.2020.4583 |pmid=32319546 |pmc=7255481 }}</ref> Specifically, the cecum and appendix are formed by the enlargement of the postarterial segment of the midgut loop. The proximal part of the bud grows rapidly to form the cecum. The lateral wall of the cecum grows much more rapidly than the medial wall, with the result that the point of attachment of the [[appendix (anatomy)|appendix]] comes to lie on the medial side.{{Citation needed|date=May 2011}} The cecum's position changes after the midgut rotates and the ascending colon elongates, and the accumulation of meconium inside the cecum may result in the latter's increased diameter.<ref name="lie"/>
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