Editing Celecoxib (section)

==Medical uses==
Celecoxib is indicated for the treatment of [[osteoarthritis]], [[rheumatoid arthritis]], [[psoriatic arthritis]], [[acute pain]], [[musculoskeletal pain]], painful [[menstruation]], [[ankylosing spondylitis]], [[juvenile rheumatoid arthritis]], and to reduce the number of colon and rectal polyps in people with [[familial adenomatous polyposis]].<ref name=AHFS2019/> It may be used in children with [[juvenile rheumatoid arthritis]] who are older than two years of age and weigh more than 10&nbsp;kg (22&nbsp;lb).<ref name=AHFS2019/>

For postoperative pain, it is more or less equal to [[ibuprofen]].<ref>{{cite journal | vauthors = Derry S, Moore RA | title = Single dose oral celecoxib for acute postoperative pain in adults | journal = The Cochrane Database of Systematic Reviews | volume = 10 | issue = 10 | pages = CD004233 | date = October 2013 | pmid = 24150982 | doi = 10.1002/14651858.CD004233.pub4 | pmc = 4161494 }}</ref> For pain relief, it is similar to [[paracetamol]] (acetaminophen) at 3990&nbsp;mg per day,<ref name="Yelland">{{cite journal | vauthors = Yelland MJ, Nikles CJ, McNairn N, Del Mar CB, Schluter PJ, Brown RM | title = Celecoxib compared with sustained-release paracetamol for osteoarthritis: a series of n-of-1 trials | journal = Rheumatology | volume = 46 | issue = 1 | pages = 135–40 | date = January 2007 | pmid = 16777855 | doi = 10.1093/rheumatology/kel195 | doi-access = free | hdl = 10072/15035 | hdl-access = free }}</ref> which is the first line treatment for osteoarthritis.<ref name=OARSI2007>{{cite journal | vauthors = Zhang W, Moskowitz RW, Nuki G, Abramson S, Altman RD, Arden N, Bierma-Zeinstra S, Brandt KD, Croft P, Doherty M, Dougados M, Hochberg M, Hunter DJ, Kwoh K, Lohmander LS, Tugwell P | title = OARSI recommendations for the management of hip and knee osteoarthritis, part I: critical appraisal of existing treatment guidelines and systematic review of current research evidence | journal = Osteoarthritis and Cartilage | volume = 15 | issue = 9 | pages = 981–1000 | date = September 2007 | pmid = 17719803 | doi = 10.1016/j.joca.2007.06.014 | doi-access = free }}</ref><ref>{{cite journal | vauthors = Flood J | title = The role of acetaminophen in the treatment of osteoarthritis | journal = The American Journal of Managed Care | volume = 16 | issue = Suppl | pages = S48–54 | date = March 2010 | pmid = 20297877 }}</ref>

Evidence of effects is not clear as several studies done by the manufacturer have not been released for independent analysis.<ref>{{cite journal | vauthors = Puljak L, Marin A, Vrdoljak D, Markotic F, Utrobicic A, Tugwell P | title = Celecoxib for osteoarthritis | journal = The Cochrane Database of Systematic Reviews | volume = 5 | pages = CD009865 | date = May 2017 | issue = 7 | pmid = 28530031 | pmc = 6481745 | doi = 10.1002/14651858.CD009865.pub2 }}</ref>

===Familial adenomatous polyposis===
It has been used to reduce colon and rectal polyps in people with familial adenomatous polyposis, but it is not known if it decreases rates of [[cancer]],<ref name=AHFS2019/> so it is not a good choice for this reason.<ref name=AHFS2019/>