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Chorionic villus sampling
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==Indications== Possible reasons for having a CVS can include:{{cn|date=February 2025}} *Abnormal first trimester screen results *Increased [[nuchal translucency]] or other abnormal [[obstetric ultrasonography|ultrasound]] findings *Family history of a [[chromosomal abnormality]] or other [[genetic disorder]] *Parents are known carriers for a [[genetic disorders|genetic disorder]] * Advanced maternal age (maternal age above 35). AMA is associated with increase risk of [[Down's syndrome]] and at age 35, risk is 1:400.{{citation needed|date=February 2020}} Screening tests are usually carried out first before deciding if CVS should be done.
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