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Chromosomal inversion
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== Detection == [[Cytogenetic]] techniques may be able to detect inversions, or inversions may be inferred from [[genetic analysis]]. Nevertheless, in most species, small inversions go undetected. More recently, comparative genomics has been used to detect chromosomal inversions, by mapping the genome.<ref name=":22">{{cite journal | vauthors = Huang K, Rieseberg LH | title = Frequency, Origins, and Evolutionary Role of Chromosomal Inversions in Plants | journal = Frontiers in Plant Science | volume = 11 | pages = 296 | date = 2020 | pmid = 32256515 | pmc = 7093584 | doi = 10.3389/fpls.2020.00296 | doi-access = free }}</ref><ref name=":02">{{cite journal | vauthors = Kirkpatrick M | title = How and why chromosome inversions evolve | journal = PLOS Biology | volume = 8 | issue = 9 | pages = e1000501 | date = September 2010 | pmid = 20927412 | pmc = 2946949 | doi = 10.1371/journal.pbio.1000501 | doi-access = free }}</ref> Population genomics may also be used to detect inversions, using areas of high [[linkage disequilibrium]] as indicators for possible inversion sites. Human families that may be carriers of inversions may be offered [[genetic counseling]] and [[genetic testing]].<ref>{{cite book | vauthors = Gardner R, Sutherland GR, Shaffer LG |title=Chromosome Abnormalities and Genetic Counseling |publisher=Oxford University Press |year=2011 |isbn=978-0-19-974915-7 |edition=4th |pages=161β182 |chapter=9 Inversions |chapter-url=https://books.google.com/books?id=mqNpAgAAQBAJ&pg=PA161}}</ref>
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