Editing Corticosteroid (section)

==Classes==
[[Image:{{wikidata|property|raw|Q190875|P117}}|thumb|200px|class=skin-invert-image|[[Cortisol]]]]
[[Image:{{wikidata|property|raw|Q423185|P117}}|thumb|200px|class=skin-invert-image|[[Cortisone]]]]
[[Image:{{wikidata|property|raw|Q422543|P117}}|thumb|200px|class=skin-invert-image|[[Corticosterone]]]]
[[Image:{{wikidata|property|raw|Q184564|P117}}|thumb|200px|class=skin-invert-image|[[Aldosterone]]]]
* '''[[Glucocorticoid]]s''' such as [[cortisol]] affect carbohydrate, fat, and protein metabolism, and have [[anti-inflammatory]], [[Immunosuppression|immunosuppressive]], [[Chemotherapy|anti-proliferative]], and [[Vasoconstriction|vasoconstrictive]] effects.<ref name=":1">{{cite journal | vauthors = Liu D, Ahmet A, Ward L, Krishnamoorthy P, Mandelcorn ED, Leigh R, Brown JP, Cohen A, Kim H | display-authors = 6 | title = A practical guide to the monitoring and management of the complications of systemic corticosteroid therapy | journal = Allergy, Asthma, and Clinical Immunology | volume = 9 | issue = 1 | pages = 30 | date = August 2013 | pmid = 23947590 | pmc = 3765115 | doi = 10.1186/1710-1492-9-30 | doi-access = free }}</ref> Anti-inflammatory effects are mediated by blocking the action of [[Inflammation|inflammatory mediators]] ([[transrepression]]) and inducing anti-inflammatory mediators ([[transactivation]]).<ref name=":1" /> Immunosuppressive effects are mediated by suppressing [[Type IV hypersensitivity|delayed hypersensitivity reactions]] by direct action on [[T cell|T-lymphocytes]].<ref name=":1" /> Anti-proliferative effects are mediated by inhibition of [[DNA synthesis]] and [[Epidermis|epidermal cell]] turnover.<ref name=":1" /> [[Vasoconstriction|Vasoconstrictive]] effects are mediated by inhibiting the action of inflammatory mediators such as [[histamine]].<ref name=":1" />
* '''[[Mineralocorticoid]]s''' such as [[aldosterone]] are primarily involved in the regulation of [[Water-electrolyte balance|electrolyte]] and water balance by modulating [[Ion transporter|ion transport]] in the [[Epithelium|epithelial cells]] of the [[Nephron|renal tubules]] of the [[kidney]].<ref name=":1" />