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Desloratadine
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== Medical uses == Desloratadine is used to treat [[allergic rhinitis]], [[nasal congestion]] and [[chronic idiopathic urticaria]] ([[hives]]).<ref name=AFP2003>{{cite journal | vauthors = See S | title = Desloratadine for allergic rhinitis | journal = American Family Physician | volume = 68 | issue = 10 | pages = 2015β2016 | date = November 2003 | pmid = 14655812 | url = http://www.aafp.org/afp/20031115/steps.html | access-date = 1 August 2005 | archive-date = 24 July 2005 | archive-url = https://web.archive.org/web/20050724082052/http://www.aafp.org/afp/20031115/steps.html | url-status = dead }}</ref> It is the major [[metabolite]] of [[loratadine]] and the two drugs are similar in safety and effectiveness.<ref name=AFP2003/> Desloratadine is available in many dosage forms and under many brand names worldwide.<ref>{{cite web | work = Drugs.com | url = https://www.drugs.com/international/desloratadine.html | title = Desloratadine | access-date = 4 May 2015 }}</ref> An emerging indication for desloratadine is in the treatment of [[acne]], as an inexpensive adjuvant to [[isotretinoin]] and possibly as maintenance therapy or monotherapy.<ref name=JEADV2014>{{cite journal | vauthors = Lee HE, Chang IK, Lee Y, Kim CD, Seo YJ, Lee JH, Im M | title = Effect of antihistamine as an adjuvant treatment of isotretinoin in acne: a randomized, controlled comparative study | journal = Journal of the European Academy of Dermatology and Venereology | volume = 28 | issue = 12 | pages = 1654β1660 | date = December 2014 | pmid = 25081735 | doi = 10.1111/jdv.12403 | s2cid = 3406128 }}</ref><ref name=DC2016>{{cite journal | vauthors = Layton AM | title = Top Ten List of Clinical Pearls in the Treatment of Acne Vulgaris | journal = Dermatologic Clinics | volume = 34 | issue = 2 | pages = 147β157 | date = April 2016 | pmid = 27015774 | doi = 10.1016/j.det.2015.11.008 }}</ref>
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