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Entorhinal cortex
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==Anatomy== The entorhinal cortex is a portion of the rostral [[parahippocampal gyrus]].<ref>{{Cite book |last=Martin |first=John D. |title=Neuroanatomy: Text and Atlas |publisher=McGraw Hill |year=2020 |isbn=978-1-259-64248-7 |edition=5th |location=New York |page=381}}</ref> === Structure === It is usually divided into [[medial (anatomy)|medial]] and [[lateral (anatomy)|lateral]] regions with three bands with distinct properties and connectivity running perpendicular across the whole area. A distinguishing characteristic of the EC is the lack of cell bodies where layer IV should be; this layer is called the ''Lamina dissecans''. ===Connections=== [[File:Apoe-cortical-thickness-entorhinal.jpg|thumb|right|300px|View of left entorhinal cortex (red) from beneath the brain, with front of brain at top. Artist's rendering.]] The superficial layers β layers II and III β of EC project to the [[dentate gyrus]] and [[hippocampus]]: Layer II projects primarily to [[dentate gyrus]] and hippocampal region CA3; layer III projects primarily to hippocampal region CA1 and the [[subiculum]]. These layers receive input from other cortical areas, especially associational, [[Perirhinal cortex|perirhinal]], and [[Parahippocampal gyrus|parahippocampal]] cortices, as well as [[prefrontal cortex]]. EC as a whole, therefore, receives highly processed input from every sensory modality, as well as input relating to ongoing cognitive processes, though it should be stressed that, within EC, this information remains at least partially segregated. The deep layers, especially layer V, receive one of the three main outputs of the [[hippocampus]] and, in turn, reciprocate connections from other cortical areas that project to superficial EC. ===Brodmann's areas=== * [[Brodmann area 28]] is known as the "area entorhinalis" * [[Brodmann area 34]] is known as the "area entorhinalis dorsalis"
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