Editing Excitatory postsynaptic potential (section)

==Excitatory molecules==
The neurotransmitter most often associated with EPSPs is the [[amino acid]] [[glutamate]], and is the main excitatory neurotransmitter in the [[central nervous system]] of  [[vertebrates]].<ref name="pmid10736372">{{cite journal|last=Meldrum|first=BS|title=Glutamate as a neurotransmitter in the brain: review of physiology and pathology.|journal=The Journal of Nutrition|date=Apr 2000|volume=130|issue=4S Suppl|pages=1007S–15S|pmid=10736372|doi=10.1093/jn/130.4.1007s|doi-access=free}}</ref> Its ubiquity at excitatory synapses has led to it being called ''the'' excitatory neurotransmitter. In some [[invertebrates]], glutamate is the main excitatory transmitter at the  [[neuromuscular junction]].<ref>{{cite journal |doi=10.1146/annurev.ne.19.030196.002553 |last=Keshishian |first=H|author2=Broadie K|author3=Chiba A|author4=Bate M | title=The Drosophila Neuromuscular Junction: A Model System for Studying Synaptic Development and Function| journal=Annu. Rev. Neurosci. |volume=19 |pages=545–575|year=1996 |pmid=8833454}}</ref><ref>{{cite journal|last=Samoilova|first=MV|author2=Frolova, EV |author3=Potapjeva, NN |author4=Fedorova, IM |author5=Gmiro, VE |author6= Magazanik, LG |title=Channel blocking drugs as tools to study glutamate receptors in insect muscles and molluscan neurons|journal=Invertebrate Neuroscience|date=September 1997|volume=3|issue=2–3|pages=117–126|doi=10.1007/BF02480366|s2cid=35749805}}</ref> In the [[neuromuscular junction]]  of vertebrates, EPP ([[end-plate potential]]s) are mediated by the neurotransmitter [[acetylcholine]], which (along with glutamate) is one of the primary transmitters in the central nervous system of invertebrates.<ref>{{cite web|url=http://www.wormbook.org/chapters/www_neuronalgenome/neuronalgenome.html|title=The neuronal genome of Caenorhabditis elegans|website=www.wormbook.org}}</ref>
At the same time, GABA is the most common neurotransmitter associated with IPSPs in the brain.
However, classifying neurotransmitters as such is technically incorrect, as there are several other synaptic factors that help determine a neurotransmitter's excitatory or inhibitory effects.