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Exoenzyme
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==History== Very limited information is available about the original discovery of exoenzymes. According to [[Merriam-Webster]] dictionary, the term "exoenzyme" was first recognized in the English language in 1908.<ref name=Dictionary>{{cite web |title=Merriam-Webster|url=https://www.merriam-webster.com/dictionary/exoenzyme|accessdate=2013-10-26}}</ref> The book "Intracellular Enzymes: A Course of Lectures Given in the Physiological," by Horace Vernon is thought to be the first publication using this word in that year.<ref name=Lexic>{{cite web |title=Lexic.us|url=https://www.lexic.us/definition-of/exoenzymes|accessdate=2013-10-26}}</ref> Based on the book, it can be assumed that the first known exoenzymes were [[pepsin]] and [[trypsin]], as both are mentioned by Vernon to have been discovered by scientists Briike and Kiihne before 1908.<ref name="history">{{cite web |last=Vernon|first=Horace|title=Intracellular Enzymes: A Course of Lectures Given in the Physiological|url=https://archive.org/stream/intracellularen00verngoog/intracellularen00verngoog_djvu.txt|accessdate=2013-10-26}}</ref>
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