Editing Factor VIII (section)

==Genetics==
[[File:F8 gene location.png|thumb|left|In human, the F8 gene is located on the [[X chromosome]] at position q28.]]
Factor VIII was first characterized in 1984 by scientists at Genentech.<ref>{{cite journal | vauthors = Gitschier J, Wood WI, Goralka TM, Wion KL, Chen EY, Eaton DH, Vehar GA, Capon DJ, Lawn RM | title = Characterization of the human factor VIII gene | journal = Nature | volume = 312 | issue = 5992 | pages = 326–330 | date = November 1984 | pmid = 6438525 | doi = 10.1038/312326a0 | s2cid = 4358041 | bibcode = 1984Natur.312..326G }}</ref> The gene for factor VIII is located on the [[X chromosome]] (Xq28). The gene for factor VIII presents an interesting primary structure, as another gene (''[[F8A1]]'') is embedded in one of its [[intron]]s.<ref>{{cite journal | vauthors = Levinson B, Kenwrick S, Lakich D, Hammonds G, Gitschier J | title = A transcribed gene in an intron of the human factor VIII gene | journal = Genomics | volume = 7 | issue = 1 | pages = 1–11 | date = May 1990 | pmid = 2110545 | doi = 10.1016/0888-7543(90)90512-S }}</ref>