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Global optimization
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== Applications == Typical examples of global optimization applications include: * [[Protein structure prediction]] (minimize the energy/free energy function) * [[Computational phylogenetics]] (e.g., minimize the number of character transformations in the tree) * [[Traveling salesman problem]] and electrical circuit design (minimize the path length) * [[Chemical engineering]] (e.g., analyzing the [[Gibbs free energy|Gibbs energy]]) * Safety verification, [[safety engineering]] (e.g., of mechanical structures, buildings) * [[Worst case|Worst-case analysis]] * Mathematical problems (e.g., the [[Kepler conjecture]]) * Object packing (configuration design) problems * The starting point of several [[molecular dynamics]] simulations consists of an initial optimization of the energy of the system to be simulated. * [[Spin glass]]es * Calibration of [[radio propagation models]] and of many other models in the sciences and engineering * [[Curve fitting]] like [[non-linear least squares]] analysis and other generalizations, used in fitting model parameters to experimental data in chemistry, physics, biology, economics, finance, medicine, astronomy, engineering. *[[Radiation therapy#Intensity-modulated radiation therapy (IMRT)|IMRT]] radiation therapy planning
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